Detailed Comparative Pharmacognostical and Physicochemical Evaluation of Chirabilvadiyoga w.s.r. to Bhavana (Trituration)

Chirabilvadi Yoga is a combination of four drugs Chirabilva, Arjuna, Jyotishmati and Kakanasa in powder form, each of these ingredients has solid base of previous experimental studies for their individual analgesic activity. Bhavana (trituration) is an important Samskara (process) mentioned in Ayurvedic classics by which drug may be made very potent to produce a positive results. Till date no data available on this combination Bhavita Chirabilvadi Yoga triturated seven times with Chirabilva Patra Swarasa and made dried powder. Present study is to screen the differences in pharmacognostical and pharmaceutical profile of the Chirabilvadi Yoga before and after Bhavana. After Bhavana significant changes were found in the pharmacognostical parameters like deformated rosette crystals and cluster crystal of Arjuna and broken stone cells of Arjuna, which are rarely found before Bhavana of the drug and also evaluate the differences in the pharmaceutical profile before and after Bhavana like loss on drying, ash value, acid insoluble ash, water soluble extract, methanol soluble extract, pH and HPTLC.

Pharmacognostical, Phytochemical and HPTLC Profile of Vayasthapana Gana Choorna and Vayasthapana Ghrita- A Poly-Herbal Compound

Menopausal syndrome is a grouping of signs and symptoms associated with menopause. In Ayurveda, menopause is referred to as 'Rajonivrutti' (and menopausal syndrome as Rajonivruttianubandhaja vyadhies). Menopause's long-term risks include osteoporosis, cardiac problems, and Alzheimer's disease. Aims and objective: To study the Pharmacognostic, Phytochemical and HPTLC of Vayasthapana Gana Choorna and Vayasthapana Ghrita. Material and methods: Pharmacognostic, phytochemical and HPTLC of Vayasthapana Gana Choorna and Vayasthapana Ghrita have been carried out as per standard protocol. Result: Vayasthapana Gana Choorna showed the presence of mesocarp, asicular crystals, stone cells, scleroids, brown content, starch grains, colencyma cells, rhomboidal crystals, pitted vessels, parenchyma cells, simple trichome. Phytochemical parameters showed refractive index 1.3660, specific gravity 0.913, acid value 1.285, iodine value 212.1085 and in HPTLC, Methanol extract of Vayasthapana Ghrita at 254nm showed 6 spots and at 366nm 2 spots whereas in methanol extract of Vayasthapana Gana Choorna at 254nm 5 spots and in 366nm 4 spots were present. Conclusion: The applied pharmacognostic and HPTLC method has been shown to be selective, linear, precise and accurate. The method will be useful for quality control of the raw material and pharmaceutical preparations.

Ingredients identification and quality control evaluation of phalakalyan ghrita: an ayurvedic formulation.

Infertility is defined as failure to conceive within one year or more than one year of regular & unprotected coitus. It is the most sensitive and cumbersome problem which haunts every couple. Total 10-15% of world population affected due to this problem. Among them Female is directly responsible about 40%. The sub factors of female infertility are Ovarian, Endometrial, Tubal and Uterine etc. In Ayurved so many formulation are given for Infertility. Phalakalyana Ghrita (PKG) is a commonly used and prescribed Ayurvedic poly herbal formulation in all types of Infertility. However, till date no published data is available on its analytical profile. The main aims and objectives of this study are to develop the pharmacognostical and phytochemical profile of PKG. The pharmacognostical study reveals the presence of Lignified fibres, Prismatic crystals, Borderpitted vessels, Rhomboidal crystal, Scleroids, Stone cells etc. Pharmaceutical analysis showed that the loss on drying value was 0.47% w/w, Specific gravity was 0.9133, Refractive index was 1.46, Iodine value was 48.56, Saponification value was 227.05, and Acid value was 1.29. HPTLC fingerprinting profile of PKG revealed 10 spots at 254 nm and 5 spots at 366nm.