RESUMO
Analysis of drugs and pharmaceuticals, at nano scale detection, is a challenging job and the urgent need of today and tomorrow. Capillary electrophoresis is a growing technique and developing continuously by improving in its detectors, sample preparation units and other parts. This article describes the analysis of drugs and pharmaceuticals by capillary electrophoresis at nano scale detection in various standard solutions, dosage formulations and biological samples. Nano scale detection analysis is discussed in terms of the advancement in the detectors and sample preparation methods. The coupling of the detectors and sample preparation units to capillary electrophoresis has also been discussed. Attempts have been made to evaluate the optimization strategies of capillary electrophoresis conditions to achieve the detection at nano scale. The applications of capillary electrophoresis for the analyses of simple and chiral mixtures of several drugs and pharmaceuticals at nano scale detection have been included