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J Environ Biol ; 2003 Jul; 24(3): 327-30
Artigo em Inglês | IMSEAR | ID: sea-113710

RESUMO

Male swiss mice were administered with the leaf extract of Thespesia populnea at a daily dose of 400 mg/kg body weight for 15 days and the testis were subjected to structural analysis. The structure of the seminiferous tubule in the testis of treated animal was elongated. Sertoli cells were enlarged in its structure and spermatids became round and disintegrated. It is suggested that the extract of T. populnea treatment leads to pathological changes in the seminiferous tubules, Sertoli cells and spermatids of the testis.


Assuntos
Animais , Masculino , Malvaceae/química , Camundongos , Extratos Vegetais/toxicidade , Testículo/patologia
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