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Purpose: Migraine headache is one of the oldest diseases known to mankind, affecting thousands of people throughout the world. The objective of this study is to compare the frequency of migraines in the patient group previously diagnosed with chronic hepatitis-B to the migraine frequency in the healthy control group. Materials and Methods: Patients who presented to Dicle University Hospital and who were diagnosed with chronic hepatitis-B were enrolled in the study. The viral hepatitis markers, aspartate aminotransferase (AST), alanine aminotransferase (ALT), hepatitis-b virus DNA (HBV DNA), and their levels were included in the evaluation. The control group consisted of healthy individuals with no hepatitis-B detected in the previous screenings. Chronic fatigue observed in the patient group was recorded, and the degree of fatigue was assessed according to the Visual Analogue Scale to Evaluate Fatigue Severity (VAS-F). Approval of the local ethics committee was obtained for this study. Results: The frequency of migraines in patients who tested positive for HBV DNA was significantly higher than in those who tested negative for HBV DNA (p<0.05). Chronic fatigue was also significantly higher in the study group compared to the control group (p=0.01), and their HBV DNA levels were correlated with the VAS-F score (r=0.532; p<0.001). Conclusion: Migraine was found to be correlated with fatigue and the HBV DNA ratio in chronic hepatitis B patients.
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ABSTRACT Objective Facial diplegia (FD) is a rare neurological manifestation with diverse causes. This article aims to systematically evaluate the etiology, diagnostic evaluation and treatment of FD. Method The study was performed retrospectively and included 17 patients with a diagnosis of FD. Results Patients were diagnosed with Guillain-Barré syndrome (GBS) (11), Bickerstaff’s brainstem encephalitis (1), neurosarcoidosis (1), non-Hodgkin’s Lymphoma (1), tuberculous meningitis (1) herpes simplex reactivation (1) and idiopathic (1). In addition, two patients had developed FD during pregnancy. Conclusion Facial diplegia is an ominous symptom with widely varying causes that requires careful investigation.
RESUMO Objetivo Diplegia facial (DF) é uma manifestação neurológica rara proveniente de diferentes causas. Este artigo visa avaliar sistematicamente a etiologia, avaliação diagnóstica e tratamento de DF. Método O estudo foi retrospectivo e incluiu 17 pacientes com diagnóstico de FD. Resultados Os pacientes foram diagnosticados como casos de síndrome de Guillain-Barré (SGB) (11), encefalite de tronco de Bickerstaff (1), neurosarcoidose (1), linfoma não-Hodgkin’s (1), meningite tuberculosa (1) reativação de herpes simplex (1) e causa idiopática (1). Além disto, duas pacientes haviam desenvolvido DF durante a gestação. Conclusão Diplegia facial é uma manifestação com diversas causas que requer investigação cuidadosa.