RESUMO
Background: Gullian-Barre Syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy (AIDP) with autoimmune background. The clinical management of GBS is by nerve conduction velocity (NCV) and supportive care, intravenous immunoglobulin’s (IVIG) and Plasmapheresis. We have studied the clinical outcome of Gullian-Barre Syndrome patients visiting to the tertiary care hospital in Andhra Pradesh. Material and methods: A cross sectional study was conducted in a tertiary care teaching hospital at Andhra Pradesh in 50 patients over the period of 2 years. Neurological examination like higher mental functions, cranial nerves, motor system, sensory system and autonomic system was done for all patients. Descriptive analysis of clinical presentation, type of GBS, occurrence of complications and final outcome was also done. Results: A total of 50 participants were included in the study. Majority (52%) of the study participants were aged below 40 years. Diabetes mellitus (DM) and hypertension (HTN) were the Vasa VK, Chowdary DB, Kalyani OM. Clinical outcome of Gullian-Barre Syndrome in a tertiary care teaching hospital – A prospective observational study. IAIM, 2016; 3(1): 105-109. Page 106 most common co-existing illnesses reported in 8% and 6% of study population respectively. Conclusion: The majority of the Guillain-Barre Syndrome patients recovered smoothly without going for complications. Prognostic outcome was poor in our study with increasing age and co-existing illness like diabetes mellitus or ischemic heart disease.
RESUMO
Background: Dyslipidemia and hypertension were the two widely recognized independent key risk factors for development of coronary vascular disorders (CVD). Therefore, Dyslipidemia and hypertension can serve as an easy clinical approach to know persons at greater risk for the and timely interference directed to decrease CVD events. To this purpose, we studied the correlation between dyslipidemia and hypertension and its complications among 30-70 years age group in a tertiary care hospital in Andhra Pradesh. Materials and methods: The present work was a hospital based, analytical cross sectional study conducted in the department of General Medicine in a tertiary care hospital at Andhra Pradesh over the period of two years from October 2012 to September 2014. A total of 100 HTN patients and 50 non hypertensive controls were recruited for the study. The patients were in the range of 30-70 years age group. Both known hypertensive patients who were on treatment for a varying period of time and newly diagnosed hypertensive patients were included in the study. The hypertensive and healthy controls were selected in to the study by systematic random sampling. A structured and validated designed case report form (CRF) was used for data collection. The tool was validated by including the inputs from five experts in the subject area. The blood samples were drawn from all the patients after 10 to 12 hours of fasting. FBS, PPBS and Lipid profile values were obtained as per the prescribed T.V Murali Krishna, Vijaya Kumar Vasa, V A Deepika Ponnuru. The study of correlation between dyslipidemia and hypertension and its complications in 30-70 years age group . IAIM, 2016; 3(4): 84-90. Page 85 standards. Descriptive analysis of demographic and relevant clinical parameters was done. Various serum lipid levels were considered as primary outcome variables. Categorical variables were presented as frequencies and percentages. Results: There were 100 hypertension patients and 50 controls were included in the final analysis. Among the hypertension patients 86% of them were males and 14% were females. The HDL value was lower in hypertensive patients, compared to control group (39.78±6.37 Vs 54.5±4.2). Statistically significant difference was observed in total cholesterol, LDL cholesterol, TC/HDL ratio and LDL/HDL ratio between obese and non obese as well as in CVA, IHD among hypertensive patients relatively with healthy volunteers. Conclusion: Biochemically there was significant difference was observed in total cholesterol, LDL cholesterol, TC/HDL ratio and LDL/HDL ratio between obese and non obese hypertensive patients. The similar discrepancy was noticed in CVA, IHD patient population. The HDL value was low down in all hypertensive patients compared to control group