RESUMO
Bauhinia foveolata Dalzell is an endemic tree, native to Southwest India (the Western Ghats). 13-Docosenamide wasisolated from ethyl acetate fraction, and quercetin (1), isorhamnetin (2), and odoratin-7-glucoside (3) were isolatedfrom butanol fraction of leaves. A spectroscopic analysis, including mass spectra and Nuclear Magnetic Resonance(NMR), and also comparison with reported data were used to elucidate the chemical structures of isolated compounds.Furthermore, all the isolated compounds were analyzed for 3-(4, 5-dimethylthiazol-2-yl)-5-diphenyltetrazoliumbromide -based cytotoxicity studies on human colon cancer cell lines, HT-29 and HCT-15; among all the testedcompounds, quercetin and odoratin-7-glucoside have shown a good cytotoxicity toward the selected cell lines.
RESUMO
Marine ecological niches have recently been described as "particularly promising" sources for search of new antimicrobials to combat antibiotic-resistant strains of pathogenic microorganisms. Marine organisms are excellent sources for many industrial products, but they are partly explored. Over 30 000 compounds have been isolated from marine sources. Bacteria, fungi, and cyanobacteria obtained from various marine sources secret several industrially useful bioactive compounds, possessing antibacterial, antifungal, and antimycobacterial activities. Sustainable cultivation methods for promising marine organisms and biotechnological processes for selected compounds can be developed, along with the establishment of biosensors for monitoring the target compounds. The semisynthetic modifications of marine-based bioactive compounds produce their new derivatives, structural analogs and mimetics that could serve as novel lead compounds against resistant pathogens. The present review focuses on promising antimicrobial compounds isolated from marine microbes from 1991-2013.