RESUMO
This study is conducted to evaluate the efficacy and safety of the poly herbal drug preparation “Jod Aram” in Rheumatoid arthritis patients. The ingredients are hydro alcoholic extraction of different parts of plants. Material and method: A double blind, randomized, fixed dose, placebo controlled clinical trial using “Jod Aram” was carried out on 24 (14 Patients of “Jod Aram” and 10 patients on placebo) patients of rheumatoid arthritis, who were followed up for a period of 6 months. Result: There is significant improvement in clinical variables of rheumatoid arthritis in “Jod Aram” group compared to placebo at the end of 24 weeks of randomization trial. The drug is most effective in reducing pain and tenderness in the joint as the observed p value < 0.001. It is also effective in reducing signs of inflammation and improving disability associated with arthritis. Conclusion: This randomized drug trial demonstrated potential efficacy, safety in symptomatic treatment of rheumatoid arthritis over 24 weeks.