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Indian J Biochem Biophys ; 1998 Apr; 35(2): 108-14
Artigo em Inglês | IMSEAR | ID: sea-26252

RESUMO

Proton magnetic resonance Spectroscopy (PMRS) has been used to study the differences between immortalized fibroblasts and fibrosarcoma cells of different grade. One and two dimensional purged correlation spectroscopy (PCOSY) have been used to assess intact viable fibroblast and fibrosarcoma cells, and differences in the triglyceride, cellular metabolite, and cell surface fucosylation patterns between the three cell lines have been observed. The clinical implication of this study is the potential use of PMRS as an adjunct to conventional histopathology.


Assuntos
Células 3T3/citologia , Aminoácidos/metabolismo , Animais , Ciclo Celular , Linhagem Celular Transformada , Membrana Celular/metabolismo , Sobrevivência Celular , Fibrossarcoma/metabolismo , Fucose/análise , Espectroscopia de Ressonância Magnética/métodos , Camundongos , Fosfolipídeos/metabolismo , Triglicerídeos/metabolismo , Células Tumorais Cultivadas
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