Study on pilot manufacture of aspirine microgelules

Announcement of some initial results of making and investigating some particularizes of aspirin microfollicle. Percentage of asprin between theory and reality has remarkable change (+16.57 to -1.37). In generally, the microcapsules sample have low rate of Asp/EC, the aspirin microencapsulated rate is high and vice versa. Parameters of asparin percentage, rate of Asp/EC influence on asparin microencapsulated rate. Asparin capsule with EC box can be made with relatively high microencapsulated rate productivity. Aspirin capsule can last liberation of pharmaceutical material and give long-lasting effect in systems

Study on membrane enveloping pellet of chlorpheniramine SR

Compounding pellet chlorpheniramin TDKT and builing its formulary from pellet were studied. The result: the optimal formule of memberance prolonging release of chlorpheniramin from pellet was selected. This memberance could quicktly release a part of primary subtance in order to immediately solve alergic symptoms. The rest release constantly prolong in 8 hours

Use accurately sustained release dosage forms

Sustained release dosage forms belong to new forms with innovative bioavailability, in which drug was released in tailored design. If physicians haven't a firm grasp on nature, composition of dosage form and give incorrect instruction for use, model of release dosage of drug will be changed, and drug is not only less effective but also harmful. Author introduced technical rules of preparing sustained release drugs, sustained release dosage forms and pathways of administration

Clinical tests of theophylline tablets with release effect prepared by the Hanoi Pharmaceutical college

The study conducted on bronchial asthmatic patients treated at Allergic Clinic in Bach Mai Hospital. The patients treated by theophylline pill acting within 12 hours, manufactured by Hanoi College of Pharmacy combined with Central Pharmaceutical Factory No. 2, used single-blind, controlled method. The patients used 200mg dose, twice in day (8 a.m and 8 p.m), separated from each other 12 hours. Results: The change of respiratory functions are good, both groups are more than 15 percentage

Dissolution test for some chloramphenicol capsule sample

This study was aimed to assess the dissolution of 4 chloramphenicol capsule products of 4 Vietnamese pharmaceutical enterprises. The results showed that most of them have a very low drug release degree. The cause may be resulted from making capsule without making particles, too raw powder, using too much insoluble excipient, too high rate of insoluble excipient. The dissolution test should be considered an item of chloramphenicol capsule specification