RESUMO
The seroprevalence of hepatitis C virus [HCV] specific antibodies and HCV genotypes distribution were studied among 559 Iraqi children with thalassaemia in receipt of repeated blood transfusions. HCV-specific antibodies were detected in 376 [67.3%] serum samples using third-generation enzyme immunoassay and confirmatory immunoblot assays. Of 78 randomly selected sera, 48 [61.5%] were HCV-RNA positive. HCV genotypes 1a, 1b, 4 and mixed 1b and 4 were demonstrated in 13 [27.1%], 11 [22.9%], 17 [35.4%] and 7 [14.6%] sera respectively. Strict measures for the controlling the spread of HCV are needed by introducing advanced techniques for blood donor screening
Assuntos
Criança , Humanos , Hepacivirus/imunologia , Immunoblotting , Anticorpos Anti-Hepatite C/sangue , Prevalência , Talassemia beta/epidemiologiaRESUMO
To estimate the seroprevalence of HCV infection among HIV-infected haemophiliacs and to demonstrate the most prevalent HCV genotype, 47 HIV-infected haemophilia patients were screened for anti-HCV antibodies. By performing polymerase chain reaction and DNA enzyme immunoassay, HCV-RNA was detected with subsequent genotyping. Seroprevalence of anti-HCV antibodies was 66.0%. Of 31 HCV/HIV co-infected patients, 21 [67.7%] had no history of blood transfusion. We detected 4 HCV genotypes: 1a, 1b, 4 and 4 mixed with 3a, HCV-1b being the most frequent. Contaminated factor VIII [clotting factor] could be responsible for disease acquisition
Assuntos
Adulto , Adolescente , Criança , Humanos , Pessoa de Meia-Idade , /epidemiologia , Hemofilia A/complicações , Genótipo , Reação em Cadeia da Polimerase , Sorotipagem/epidemiologiaRESUMO
To determine the age incidence and prevalence of Pityrosporum orbiculare on the normal skin of healthy Iraqi children, we carried out a survey of clinically normal skin of 110 healthy children in Baghdad during April 1998-October 1998. We isolated P. orbiculare on a peptone--glucose--yeast extract medium containing chloramphenicol and cycloheximide, and overlaid with olive oil. The organism was present on the trunk in 77.5% of children 10-14 years, 27.5% of children 5-9 years, and 6.6% of children < 5 years
Assuntos
Criança , Humanos , Lactente , Adolescente , Distribuição por Idade , Pré-Escolar , Meios de Cultura , IncidênciaRESUMO
Sera from 3491 pregnant women were screened for the presence of HCV antibodies [anti-HCV]. HCV genotyping was also performed on the sera of 94 women. The overall anti-HCV seroprevalence was 3.21%. Anti-HCV seroprevalence was significantly positively correlated with the number of miscarriages. Miscarriage was a significant risk factor for the acquisition of HCV infection from the first miscarriage up to the fifth, the risk increasing with increasing number of miscarriages. A higher proportion of women with a history of miscarriage harboured HCV-1b compared to those with no miscarriage