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ABSTRACT Introduction: The exercise of functional strength in a sprinter can play an essential performance gain to propulsion. Functional training can significantly affect the sprinter, preventing injury and making better use of physical training. The sprint interval training method has been widely recognized and applied. Objective: This paper explores the effect of functional strength training by the sprint interval training method on the strength quality of sprinters. Methods: This paper uses random sampling to select 30 male college sprinters as research subjects. The volunteers were divided into two groups according to the performance of the 100-meter speed project: All the essential data of the subjects who passed the T-test were without statistical difference P>0.05. Both groups perform daily training. Functional strength training was added to the experimental group by interval start training with a full 12-week cycle. The strength data of the athletes were measured before and after the experiment, measured, and discussed statistically. Results: The indicators showed significant differences, except for the normal left supine position support test, unchanged by the presented intervention(P<0.01). After the experiment, all indicators were statistically significant compared to the control group (P<0.01). The performance of the groups in the ball exercise, static jump, and vertical jump was significantly improved (P<0.01). Conclusion: Functional strength exercise can improve sprinters' body control and stability. The sprint interval method can also improve the speed of upward force transmission. This conclusion is significant for formulating the strength training plan designed for sprinters. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
RESUMO Introdução: O exercício da força funcional no velocismo pode desempenhar um ganho de performance essencial à propulsão. O treinamento funcional pode afetar significativamente o velocista, tanto na prevenção de lesões quanto ao melhor aproveitamento do treinamento físico. O método de treinamento intervalado de arranque tem sido amplamente reconhecido e aplicado. Objetivo: Este artigo explora o efeito do treinamento de força funcional pelo método de treinamento intervalado de arranque sobre a qualidade da força dos velocistas. Métodos: Este artigo usa amostragem aleatória para selecionar 30 velocistas universitários masculinos como objetos de pesquisa. Os voluntários foram divididos em dois grupos de acordo com o desempenho do projeto de 100 metros de velocidade: Todos os dados essenciais dos sujeitos que passaram no teste T foram sem diferença estatística P>0,05. Ambos os grupos realizam um treinamento diário. Ao grupo experimental foi acrescentado o treinamento de força funcional pelo treinamento intervalado de arranque com ciclo completo de 12 semanas. Os dados de força dos atletas foram mensurados antes e após o experimento, mensurados e discutidos estatisticamente. Resultados: Os indicadores demonstraram diferenças significativas, exceto para o teste normal de apoio à posição supina esquerda, inalterado pela intervenção apresentada (P<0,01). Após o experimento, todos os indicadores foram estatisticamente significativos em comparação com o grupo controle (P<0,01). O desempenho dos grupos em exercício de bola, salto estático e salto vertical foram significativamente aprimorados (P<0,01). Conclusão: O exercício de força funcional pode melhorar o controle e a estabilidade corporal dos velocistas. O método de treinamento intervalado de arranque também pode melhorar a velocidade de transmissão de força ascendente. Essa conclusão é significativa para a formulação no plano de treinamento de força destinado à velocistas. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.
RESUMEN Introducción: El ejercicio de la fuerza funcional en los velocistas puede suponer una ganancia de rendimiento esencial para la propulsión. El entrenamiento funcional puede afectar significativamente al velocista, tanto en la prevención de lesiones como en el mejor aprovechamiento del entrenamiento físico. El método de entrenamiento por intervalos de sprint ha sido ampliamente reconocido y aplicado. Objetivo: Este artículo explora el efecto del entrenamiento de fuerza funcional mediante el método de entrenamiento de intervalos de sprint en la calidad de la fuerza de los velocistas. Métodos: Este artículo utiliza un muestreo aleatorio para seleccionar 30 velocistas universitarios como sujetos de investigación. Los voluntarios se dividieron en dos grupos según el rendimiento del proyecto de velocidad de 100 metros: Todos los datos básicos de los sujetos que superaron el test-T fueron sin diferencia estadística P>0,05. Ambos grupos realizan un entrenamiento diario. Al grupo experimental se le añadió el entrenamiento de fuerza funcional por intervalos de sprint con un ciclo completo de 12 semanas. Los datos de fuerza de los atletas se midieron antes y después del experimento, y se analizaron estadísticamente. Resultados: Los indicadores mostraron diferencias significativas, a excepción de la prueba normal de apoyo a la posición supina izquierda, no modificada por la intervención presentada (P<0,01). Tras el experimento, todos los indicadores fueron estadísticamente significativos en comparación con el grupo de control (P<0,01). El rendimiento de los grupos en el ejercicio con balón, el salto estático y el salto vertical mejoró significativamente (P<0,01). Conclusión: El ejercicio de fuerza funcional puede mejorar el control corporal y la estabilidad de los velocistas. El método de entrenamiento por intervalos de sprint también puede mejorar la velocidad de transmisión de la fuerza ascendente. Esta conclusión es significativa para la formulación en el plan de entrenamiento de fuerza para los velocistas. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.
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Abstract@#In order to improve the prevention and control of myopia, this paper examines the significance of hyperopia reserves and its correct application, identifies problems requiring further attention and sums up past experiences. It puts forward a prevention and control system of myopia after introduction of the physiotherapy instruments, especially those based on the principle of red light. This paper discusses some mechanisms of low concentration atropine eye drops in preventing and controlling myopia. Finally, future research directions are proposed.
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Objective @#To improve the dentist's understanding of desmoplastic fibroma of the jaw, we investigated the clinical manifestations, pathological features, treatment and prognosis of this disease.@*Methods@#The clinical data of 8 patients with desmoplastic fibroma of the jaw who were admitted to Nanjing Stomatological Hospital from 2011 to 2021 were retrospectively reviewed.@* Results @#The male-female ratio in this group was 3:1, the age of first onset was 32.13±15.00, and the lesions were mainly in the mandible. Histologically, the lesions was composed of mildly atypical fibroblasts and a large number of collagen fibers. The positive rates of Vimentin, α-SMA and β-catenin in the cytoplasm were 100%, 62.5% and 62.5%, respectively. The Ki-67 level in the initial patients was lower than 5%, and the S-100 protein level was 100% negative. The imaging manifestations were single-room or multichamber light-transmitting lesions with clear or irregular boundaries, with or without peripheral sclerosis. Five patients were treated with curettage for the first time; among them, two patients relapsed with poor prognosis. Three patients underwent extended resection, and all had no recurrence.@*Conclusions @# The clinical and imaging features of desmoplastic fibroma of the jaw are not specific. We mainly rely on histopathology to diagnose the disease. It has a high recurrence rate after surgery. At present, the best treatment is to extend surgical resection. Local curettage is easy to relapse and has a poor prognosis.
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Objective@#To describe bullying victimization of middle school students in Dalian and associated factors, so as to provide scientific basis for campus bullying prevention.@*Methods@#The stratified cluster sampling method was used to select 2 540 middle school students from urban and rural areas in Dalian, who were investigated with campus bullying victimization and related factors.@*Results@#The reported rate of campus bullying victimization among middle school students in Dalian was 25.11%. The rates of physical violence (5.99%, 3.66%) and verbal violence(24.93%, 15.87%) of male students were higher than that of female students( χ 2=6.56, 27.94, P <0.05). The rates of verbal violence (22.84%, 16.25%) and emotional neglect(16.84%, 13.18%) of junior high school students were higher than those of high school students( χ 2=14.21, 5.44, P < 0.05 ). The rates of physical violence(6.07%, 3.55%), verbal violence(24.58%, 16.05%) and emotional neglect(18.88%, 12.06 %) of rural students were higher than those of urban students( χ 2=7.72, 24.81, 19.64, P <0.05). Male students, junior high school students and rural students suffered more severe campus bullying than female students, high school students and urban students( Z =3.46, 3.75, 5.89, P <0.01). The structural equation model showed that academic performance (path coefficient -0.003) and father s education (path coefficient -0.004 ) have a direct negative effect on campus bullying behavior, while mother s education (indirect action coefficient -0.000 8), height(indirect action coefficient -0.000 3), father s education (indirect action coefficient -0.000 3) and weight (indirect action coefficient 0.000 2) indirect effects on campus bullying through academic performance.@*Conclusion@#The prevalence of campus bullying victimization among middle school students in Dalian is relatively high, which worths further attention to. Rural students, junior high school students and boys are more likely to suffer campus bullying. Improving academic performance might be beneficial for campus bullying prevention.
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Abstract@#It is necessary to manage various visual environments for myopia prevention and control. This paper systematically collected relevant domestic standards, including local standards and group standards. Based on the authors’ research experience, relevant educational appliance and equipment standards primarily focused on exercise books, textbooks, luminaires and exam papers. In addition, this paper analyzed the indicators and health requirements related to vision protection of electronic reading materials, extracurricular reading materials, newspaper, lighting and table lamp.
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Abstract@#At present, the burden of multiple preventable health problems challenging children and adolescents are generally increasing. Firstly, this paper makes an in-depth analysis of the underlying nature and seven characteristics of health issues among children and adolescents, including universality, importance, programming, irreversibility, family nature, clustering, and relevance. Abundant examples are provided for a better understanding. This paper further puts forward the following three countermeasures, advocating prevention over control, deep integration of education and health, and individualized health education. Examples are presented for deep understanding and operability of the proposed strategies.
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Summary Objective: Nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S) were endogenously-generated molecules gas. They owned important biological activity and participated in many pathophysiological processes. This study aimed to examine the levels of three gasotransmitters in the early phase of trauma patients. Method: Blood samples were collected from 60 trauma patients and ten healthy volunteers. Concentration of serum iNOS and HO-1 were analyzed by enzyme linked immunosorbent assay and plasma H2S was determined by colorimetric method. Meanwhile, the occurrence of multiple organ dysfunction syndrome (MODS) was also monitored. Results: The levels of iNOS, HO-1 and endogenous H2S in the patients group were significantly different from the healthy control group, and the difference was more obvious with the increase of ISS score. iNOS levels were positively correlated with ISS scores and blood lactic acid values, and HO-1 and endogenous H2S were negatively correlated with ISS scores and blood lactic acid values. Of 60 trauma patients, eight (13.33%) developed MODS. The level of iNOS in the MODS group was higher than that in non-MODS group, while HO-1 and H2S were significant lower in the MODS group. Conclusion: The three gasotransmitters participated in systemic inflammatory responses during early trauma and could be used as important indicators for trauma severity. Their measurements were meaningful for evaluating the severity and prognosis of trauma.
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Humanos , Masculino , Feminino , Adolescente , Adulto , Adulto Jovem , Ferimentos e Lesões/sangue , Monóxido de Carbono/sangue , Gasotransmissores/sangue , Sulfeto de Hidrogênio/sangue , Óxido Nítrico/sangue , Ensaio de Imunoadsorção Enzimática , Biomarcadores/sangue , Estudos de Casos e Controles , Índices de Gravidade do Trauma , Pessoa de Meia-IdadeRESUMO
<p><b>OBJECTIVE</b>To study the applied value of double joystick technique in reduction-internal fixation for femoral shaft fracture in adults.</p><p><b>METHODS</b>Thirty-four patients (24 males and 10 females) with femoral shaft fractures were treated with reduction assisted by double joystick technique and internal fixation with interlocking intramedullary nail from September 2010 to June 2013. The average age of the patients was 41 years old, ranged from 17 to 65 years old. The duration of the disease course ranged from 3 to 7 days, with a mean of 5 days. The fractures belonged to AO types 32A (5 cases), 32B (20 cases) and 32C (9 cases) and located in left femur for 18 patients and right femur for 16 patients. The patients were followed up, and fracture healing and complications were observed. The curative effect were evaluated according to Thorsen femur fracture evaluation standard.</p><p><b>RESULTS</b>The operative time ranged from 40 to 110 min (mean 75 min) and intraoperative blood loss ranged from 200 to 300 ml (mean 250 ml). All the patients obtained a good fracture reduction and were followed up for 12 to 24 months (mean 18 months) after the surgery. All the fractures united between 4 and 8 months with a mean of 5 months. No complications such as breakage of nail, infection, osteofascial compartment syndrome, refracture and fracture malunion were found. According to Thorsen femur fracture evaluation standard, 30 patients obtained an excellent result, 3 good and 1 fair.</p><p><b>CONCLUSION</b>In surgery of reduction-internal fixation for femoral shaft fracture in adults, the use of double joystick technique obtains good reduction result, short operative time, less injury, high healing rate of bone fractures, less complications and good limbs function, so it is worthy of popularizing in clinic.</p>
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Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Pinos Ortopédicos , Fraturas do Fêmur , Cirurgia Geral , Fixação Intramedular de Fraturas , Métodos , Consolidação da FraturaRESUMO
We studied the regulatory effects of the estragen receptorβ(ERβ)gene on the downstream estrogen signal transfection pathway in colon cancer cells and the possible mechanisms involved.A human ERβ gene recombinant expression plasmid,pEGFP-C1-ERβ,was constructed and transfected into the Caco-2 colon cancer cell line,a line with low ERβ gene expression.The expression of ERβmRNA and protein was detected 72 h after transfection.RT-PCR was used to examine the expression levels of the progesterone recepror(PR)gene containing the classic estrogen response element(ERE),the C-fos oncogene containing the AP-1 site(a non-classical ER binding site),the epigenetic modifying genes,such as Dnmt1,Dnmt3a,Dnmt3b,and histone methyltransferase(HMT),and the human mismatch repair gene hMLH1.Methylation-specific PCR was used to detect the changes in the methylated sites of the CpG islands in the promoters of the ERβ,PR,and C-fos genes.The results indicated that the human ERβ gene recombinant expression plasmid pEGFP-C1-ERβ was successfully constructed and transfected into Caco-2 cells.As compared with the control group,the mRNA and protein expression of ERβ gene was increased significantly 72 h after the transfection of pEGFP-C1-ERβ into the Caco-2 cells.As compared with the control group,the mRNA expression of the PR,C-fos,Dnmt3a and Dnmt3b genes was increased significantly 72 h after the transfection of pEGFP-C1-ERβ into the Caco-2 cells,but the mRNA expression of the Dnmt1,HMT,and hMLH1 genes decreased significantly(P<0.05).As compared with the control group,different degrees of demethylation occurred in the promoters of the ERβ,progesterone receptor(PR),and C-fos oncogene 72h after the transfection of pEGFP-C1-ERβ into the Caco-2 cells.The methylation index of the estrogen signal transfection pathway in Caco-2 cells was decreased significantly following the expression restoration of ERβ gene(P<0.05).It is concluded that the restoration or up-regulation of the ERβ gene in Caco-2 cells may significantly activate the expression of the related target genes in the downstream estrogen signal transfection pathway and may result in the demethylation changes of the pathway.During the process,the expression level and activity of the epigenetic modifying genes and the human mismatch repair gene have changed simultaneously.The regulatory effect of the ERβ gene on the estrogen signal transfection pathway to a certain extent partly involves demethylation.
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<p><b>OBJECTIVE</b>To observe the effect of different needling manipulation in improvement of swallow-period obstacle of dysphagia after stroke.</p><p><b>METHODS</b>One hundred and eleven cases were randomly divided into a single Lianquan RN 23 shallow needling group (group A ), single Lianquan (RN 23) deep needling group (group A2) and Lianquan (RN 23) and para-Lianquan deep multi-needling group (group B). The therapeutic effect was investigated after continuous treatment for 14 days.</p><p><b>RESULTS</b>The total effective rate was 95. 0% in the group B, 65. 7% in the group A1 and 83. 3% in the group A2, with significant difference or very significant difference when the group B compared with the group A, and the group A, (P<0. 01 or P<0. 05); the cured and markedly effective rate was 82. 5% in the group B, 20. 0% in the group Al and 52. 8% in the group A2, with a very significant difference as the group B compared with the group A, and A2 (both P<O. 01). After treatment for 7 days, there were very significant differences in scores of swallow function as the group B compared with the group A, and A2 (both P<0. 01), indicating that the group B was better than the group A1 and AZ in improvement of sensitivity of swallow dysphagia.</p><p><b>CONCLUSION</b>Deep needling with multi-needles can significantly improve swallow-period obstacle of dysphagia after stroke with higher safety and rapid effect.</p>