Isolation and identification of the chemical constituents from cortex of african traditional medicinal Pausinystaliamacroceras P / 中国药学杂志

OBJECTIVE: To study the chemical constituents from cortex of African traditional medicine Pausinystalia macroceras P. METHQDS: Various column chromatographic techniques were used to isolate and purify the chemical constituents and their structures were elucidated by spectral analysis and chemical analysis. RESULTS: Nine compounds were isolated and identified as corynan-theidine(I), corynantheine(II), ajmalicine(III), yohimbine(IV), corynanthine(V), α-yohimbine(VI), α-yohimbine(VII), β-sitosterol(VI), ursolic acid(IX) and oleanolic acid(X). CONCLUSION: The compounds I, IV, VIII, IX and X are isolated from Pausinystalia macroceras P. for the first time.