1.
Acta Pharmaceutica Sinica
; (12): 135-43, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-414946
RESUMO
Bacterial communities usually develop biofilms abound in nature niche. The development of biofilm is a highly dynamic and complex process coordinated by multiple mechanisms, of which two-component system and quorum sensing are two well-defined systems. Biofilm is involved in the virulence of many pathogens. Therefore, targeting the key factors involved in the biofilm formation represents a novel and promising avenue for developing better antibiotics.