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1.
Artigo em Inglês | IMSEAR | ID: sea-159962

RESUMO

Setting: Tiruvallur district In Tamil Nadu where DOTS was implemented by the State Government as the tuberculosis control measure in 1999, and monitored by the National Institute for Research in Tuberculosis for over five years. Objective: To estimate trends in TB prevalence in a rural community with DOTS. Design: Surveys of pulmonary tuberculosis were undertaken in representative samples of subjects aged >15 years (N = 83,000 – 92,000), initially and after two and half, five and seven and half years of implementation of DOTS. Sputa were collected from those with abnormal radiograph and/or presence of chest symptoms, and examined by direct smear and culture. Results: The prevalence of culture-positive tuberculosis was 607, 454, 309 and 388 per 100,000 in the four surveys, and that of smear-positive tuberculosis was 326, 259, 168 and 180. In the first five years; annual decrease was 12.4% (95% CI 10.4 - 14.4%) for culture-positive tuberculosis, and 12.2% (95% CI 8.0–16.2) for smear-positive tuberculosis. This was, however, followed by a significant increase in the next two and half years. The average new smear-positive case-notification rate was 75 per 100,000 during first four years but declined to 49 in subsequent years. There were no methodological differences during this period and information on changes in socio-economic indicators and nutritional standards was unavailable. Conclusion: Despite the average annual success rate (78%) in this tuberculosis unit being lower than the expected rate of 85%, the implementation of DOTS was followed by a substantial decrease in the prevalence of pulmonary tuberculosis over the seven and half year period. Our findings suggest that sustaining the high effectiveness of DOTS programme needs vigilant supervision.


Assuntos
Adolescente , Antituberculosos/uso terapêutico , Terapia Diretamente Observada , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Prevalência , Radiografia Torácica , Escarro/microbiologia , Tuberculose Pulmonar/diagnóstico , Tuberculose Pulmonar/tratamento farmacológico , Tuberculose Pulmonar/epidemiologia
2.
Dement. neuropsychol ; 5(2)jun. 2011.
Artigo em Português | LILACS | ID: lil-592307

RESUMO

Alzheimers disease (AD) is the most common cause of dementia in the elderly. Efforts to determine risk factors for the development of AD are important for risk stratification and early diagnosis. Furthermore, there are no standardized practices for memory screening. Lack of knowledge on AD, perception of memory loss as part of normal aging, and poor socioeconomic conditions may also be implicated in the current situation of dementia. Objective: To evaluate knowledge of AD in a literate population of elders and correlate these findings with sociodemographic characteristics. Methods: A descriptive survey design study enrolled 994 volunteers from September 2007 to May 2008 in the city of Santos, São Paulo, Brazil, to answer a brief questionnaire consisting of 8 simple questions about knowledge of AD and worries about memory loss. Results: Greater knowledge about AD was associated with eight or more years of education, female gender and age between 60 and 70 years. Also, 52.8% of responders (95% CI - 49.5-56.0%) answered that memory loss is part of normal aging and 77.5% (95% CI - 74.7-80.1%) had never sought a doctor to evaluate their memories. Conclusion: Our study results reinforced that the first line of preventing late diagnosis of dementia is to act in health promotion, especially by targeting subjects older than 70 years of male gender and with lower educational level. It also provided evidence that strategies to promote physician initiative in treating memory problems are also paramount.


A doença de Alzheimer (DA) é a causa mais comum de demência. Determinar os fatores de risco para o desenvolvimento da DA é importante na estratificação de risco e no diagnóstico precoce. Falta de conhecimento sobre a DA, percepção de perda de memória como parte do envelhecimento normal e más condições de socioeconômicas podem também estar implicadas. Objetivo: Avaliar o conhecimento sobre DA numa população alfabetizada de idosos e correlacionar esses achados com suas características sociodemográficas. Métodos: Este estudo descritivo envolveu 994 voluntários de Setembro de 2007 a Maio de 2008 na cidade de Santos, São Paulo, Brasil. Eles se dispuseram a responder um questionário simples composto de 8 questões sobre o conhecimento da DA e preocupações com a perda de memória. Resultados: Um maior conhecimento sobre DA foi associado à escolaridade >8 anos de estudo, ao gênero feminino e a idade entre 60 e 70 anos. Além disso, 52,8% dos respondedores (IC 95% - 49,5-56,0%) disseram que perda de memória faz parte do envelhecimento normal e 77,5% (IC 95% - 74,7-80,1%) relataram que nunca haviam procurado um médico para avaliação de memória. Conclusão: Nosso estudo reforça o fato de que a primeira linha de prevenção do diagnóstico tardio de demência é a promoção da saúde, especialmente tendo em foco indivíduos maiores de 70 anos, gênero masculino e maior escolaridade, nossa população de mais alto risco. Também traz evidências de que estratégias para promover a iniciativa dos médicos no cuidado aos problemas de memória são de grande importância.


Assuntos
Humanos , Idoso , Doença de Alzheimer , Demência , Transtornos Neurocognitivos , Estudos Epidemiológicos
3.
Artigo em Inglês | IMSEAR | ID: sea-146944

RESUMO

Setting – A Tuberculosis Unit (TU) with a population of 600,000 in Gurgaon district, Haryana. Objective - To compare the treatment success rate among TB patients taking DOT from community-based Angan-wari workers (AWWs) with that of TB patients with other DOT providers. Design - AWWs were given a two-day modular training, included in the local DOT directory and were directly supervised by the TB Programme staff. From the TB register held at the TU, treatment outcomes of all new sputum positive (NSP) patients registered in Gurgaon TU from 1st January to 31st December 2002, were evaluated. Results - During 2002, AWWs observed the treatment of 115 (11%) patients in the TU. The cure rate amongst the 41 NSP patients, who had AWWs as DOT providers, was significantly better than for those who had other DOT providers (95% vs. 78%) respectively (p=0.02). Conclusion - Community-based Angan-wari workers, with adequate training and regular supervision, can contribute effectively to a TB programme as DOT providers.

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