Comparison of surgical effects between extension and flexion type of distal radius fracture / 中国骨伤

OBJECTIVE@#To compare therapeutic effects of internal fixation with volar locking plate in treating extension and flexion type of distal radius fracture (DRF).@*METHODS@#From January 2015 to June 2018, 103 patients with DRF were retrospectively analyzed. According to original fracture displacement direction, patients were divided into extension fracture(Colles) group and flexion fracture (Smith) group. In Colles fracture group, there were 24 males and 44 females aged from 20 to 79 years old with an average of (59.0±13.4) years old;according to AO classification, 9 patients of type A2, 13 patients of type A3, 16 patientsof type C1, 17 patients of type C2 and 13 patients of type C3;the time from injury to operation ranged from 2 to 9 days with an average of (3.9±0.8) days. In Smith fracture group, there were 15 males and 20 females, aged from 27 to 87 years old with an average of (60.1±15.3) years old;according to AO classification, 4 patienst of A2, 7 patients of A3, 14 patients of C1, 5 patients of C2 and 5 patients of C3;the time from injury to operation ranged from 2 to 6 days with an average of (4.1±0.9) days. Operation time, fracture healing time and postoperative complications were recorded between two groups. Disabilities of arm, shoulder and hand (DASH) score at 6 and 8 weeks, 6 and 8 months were used to evaluate functional recovery of affected limbs during each follow up. Volar tilt, radial inclination and radius height were measured at 8 months after operation. Mayo score was measured at 8 months after operation to evaluate recovery of limb function.@*RESULTS@#All patients were followed up for 8 to 30 months with an average of (14.8±4.3) months, and no difference in follow up between two groups (@*CONCLUSION@#Patients with Colles fracture and Smith fracture could receive good reduction and fixation through volar locking plate. The radiographic parameters of both groups recovered satisfactorily after operation. Recovery of volar tilt of Smith fracture group is better than that of Colles fracture group, and early recovery function of Colles fracture group is better than that of Smith group, but there is no significant difference in long-term wrist joint function and incidence of postoperative complications between two groups.

Correlation between the incidence of hip fractures and the proximal femur by 3D geometric anatomy / 医用生物力学

Objective To measure the hip anatomic parameters and explore the differences between the hip fracture group and the normal group, analyze their effect on the incidence of hip fractures and fracture types by using computer aided design (CAD) and three-dimensional reconstruction technique. Methods Through CT scan images from the lower-extremity of hip fracture patient, the 3D anatomic model was established by Mimics10.01 software, and the 3D anatomic parameters of the normal proximal femur, namely femoral neck anteversion angle (FNAA), neck-shaft angle (NSA), femoral head diameter (FHD), length of femoral neck axis (LFNA) in the lower-extremity were measured. Results The averages of FNAA, NSA, FHD, LFNA in femoral neck fracture group were (7.9±4.6)°, (128.6±4.6)°, (46.0±4.6) mm, (47.1±5.1) mm, and those parameters in intertrochanteric fracture group were (15.5±6.8)°, (134.7±6.9)°, (45.3±3.6) mm, (46.7±3.4) mm. The FNAA and NSA in intertrochanteric fracture group were significantly larger than those in femoral neck fracture group regardless of gender (P<0.01). The FNAA and NSA in both fracture groups showed significant differences as compared with the normal group. ConclusionsThe risk of femoral intertrochanteric fracture will increase when the FNAA is larger than the normal range in Chinese, while the risk of femoral neck fracture will increase when the FNAA is smaller than the normal range in Chinese. The NSA of hip fracture patients was larger as compared with normal Chinese. The larger NSA will lead to a higher risk of femoral intertrochanteric fracture. There exist some differences in anatomic parameters of the proximal femur between the fracture group and the normal group, especially in the angle parameter. The femoral intertrochanteric fractures are more prone to occur in the older people, while the femoral neck fractures are more prone to occur in the younger people.

Dual cell seeding to improve cell retention on polytetrafluoroethylene grafts / 中华外科杂志

<p><b>OBJECTIVE</b>To improve cell retention on the graft with dual cell seeding technique, adding a layer of smooth muscle cells (SMCs) between the graft and endothelial cells (ECs).</p><p><b>METHODS</b>Polytetrafluoroethylene (PTFE) grafts pretreated with fibronectin were seeded with SMC followed by ECs one day later and exposure to an in vitro flow system. The number of ECs on grafts was counted under microscope.</p><p><b>RESULTS</b>After exposure to the flow for 1 hour, 61% of the ECs lost when the ECs were seeded alone, whereas only 27% of the ECs lost when the ECs were seeded on the top of SMCs. Preconditioning of a cell seeded graft in a low rate flow did not improve cell retention when late exposure to a higher rate flow.</p><p><b>CONCLUSION</b>This in vitro study indicates that using SMCs as a media layer between ECs and graft surface can improve the retention of seeded ECs on PTFE graft.</p>