RESUMO
Diabetic microangiopathy is an vital reason of disabling and death in patients with diabetes.Long-term hyperglycemia and insulin resistance in type 2 diabetes mellitus can be involved in the formation of microangiopathy by aggravating mitochondrial damage,inflammation,and protein kinase C/glycosylation end product pathways.Besides,in recent years,several studies have shown that the activation of complement system plays an important role in the progression of diabetic vascular disease (including diabetic microvascular and macrovascular disease).This review is about to discuss the role and mechanism of the complement system in the development of diabetes and its microandioathy.
RESUMO
To evaluating the imaging features and the pathological basis of low grade malignant cystic mesothelioma of the peritoneum (LGMCMP). In 14 cases of LGMCMP, radiographic imaging (X ray, CT, and MRI) was reviewed, and diagnosis was established by pathology. The majority of the patients were middle aged women. The main symptoms were abdominal pain or discomfort. CT and MRI revealed solitary cystic masses in 3 of them, multiple cystic nodules in 5, and diffuse cystic nodules in 6. It is therefore concluded that X ray, CT, and MRI are helpful in revealing the characteristics of LGMCMP and confirm the diagnosis.