Dynamic Observation and Value of Plasma Level of Thrombomodulin in Rats with Traumatic Hemorrhagic Shock / 现代检验医学杂志

Objective To explore the dynamic changes in the plasma levels of thrombomodulin(TM)with traumatic hemor-rhagic shock (THS).Methods The model of the THS with gradient decerease in the systolic blood pressure was eatablished in 1 7 rats without specific pathogen.The arterial blood during the different phase of shock,i.e.when the systolic pressures were three forth,one second,two fifth of the basis systolic blood pressure,one fifth of the basic systolic blood pressure and 10mmHg,was collected and TM levels in the plasma were determined by the double antibody sandwich method of enzyme-labeled immunosorbent assay (ELISA)and analyzed.Results There were significant differences in plasma levels of TM be-tween groups,with TM levels in T2~T3 period of time increased with the extension of time,and TM levels in T4~T5 peri-od of time decreased with the extension of time,and TM levels in T5~T6 period of time increased with the extension of time.Conclusion The animal model of THS was related to the systolic pressure during the shock,may be helpful to assess-ment changes in blood loss.The dynamic observation of the plasma levels of TM which is a good index of the damage to the vascular endothelial cells,may be helpful to assessment of the THS is related to the degree of damage to the vascular endo-thelial cells.

Creation of the idea of happy medical treatment and the principles of its development / 中华医院管理杂志

Happy medical treatment" is a new idea of the hospital. On the one hand, it stresses that the hospital should strive to reduce the pain and increase the happiness of patients; on the other hand, it pursues the goal of medical personnel working happily and enjoying happiness in their work. The creation of the idea of "happy medical treatment" results inevitably from the increasingly intensifying competition in the medical market and from the constantly rising expected value on the part of consumers. By explaining the connotations of the idea of "happy medical treatment", the paper sets forth the basic principles for the hospital to develop the new idea: permeability, systematicness and continuity. An in-depth analysis on these principles is offered.