RESUMO
The clinical, histological and immunohistochemical features of the first three cases of mammary hamartoma diagnosed at the University of the West Indies are reported. These tumours are innocuous and under-recognized although the mammographic features are characteristic. With increased utilization of this test in breast cancer detection in our region, it is likely that more of these legions will be identified.
Assuntos
Adulto , Feminino , Humanos , Doenças Mamárias , Neoplasias da Mama/patologia , Hamartoma/patologia , Mamografia , JamaicaRESUMO
A malignant triton tumour is a malignant schwannoma with rhabdomyoblastic differentiation, and is a very rare occurrence. We describe the case of a 33-year-old man with neurofibromatosis type 1 who presented with paraplegia. Pathological examination of an intradural, extramedullary tumour excised at lumbar laminectomy demonstrated a malignant schwannoma with rhabdomyoblastic differentiation. We believe this is the first documented case of a malignant triton tumour of the spine
Assuntos
Adulto , Humanos , Masculino , Neoplasias da Medula Espinal/patologia , Neurofibromatose 1/complicações , Neurilemoma/patologia , Neoplasias da Medula Espinal/cirurgia , Evolução Fatal , Laminectomia , Neurilemoma/cirurgiaRESUMO
A total of eleven (11) cases of non-parasitic splenic cysts have been studied at the University Hospital of the West Indies by routine haematoxylin and eosine and immunohistochemcial staining, using epithelial markers (cytokeratin, low molecular weight keratin and epithelial membrane antigen). The majority (eight of eleven) were found to epithelial or true cysts. This is in contrast to findings previously reported in the literature, based on light microscopic examination, that the majority of splenic cysts are non-epithelial in origin. We therefore suggest that immunohistochemical studies should be used routinely to accurately define the nature of all splenic cysts.