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Iraqi Journal of Biotechnology. 2004; 3 (1): 1-20
em Inglês, Árabe | IMEMR | ID: emr-66224

RESUMO

Trials for gene therapy were conducted on dwarf mice by using germ cells and transgenic techniques. However; the integration of the growth gene within mice genomes have led to permanent expression and mice gigantism. With the move toward the using of somatic cells instead of germ cells, two approaches were available: 1-Ex vivo gene therapy. 2- In vivo gene therapy. This article is an overview on growth gene, growth hormone and future medical applications


Assuntos
Animais de Laboratório , Hormônio do Crescimento , Terapia Genética , Camundongos , Hormônio do Crescimento/fisiologia , Receptores da Somatotropina , Hipófise/fisiologia
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