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Journal of Pathology and Translational Medicine ; : 10-16, 2016.
Artigo em Inglês | WPRIM | ID: wpr-225236

RESUMO

Menetrier's disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Menetrier's disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand, transforming growth factor alpha, contributes to the pathogenesis of this disorder. In this review, we will discuss disease entities that can mimic Menetrier's disease and the role of EGFR signaling in Menetrier's disease.


Assuntos
Gastrite Hipertrófica , Receptores ErbB , Fator de Crescimento Transformador alfa
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