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2.
Artigo em Coreano | WPRIM | ID: wpr-201755

RESUMO

Artemisia annua is a wormwood. Because it may induce Cytochrome P450 2C19 enzyme, Artemisia annua may have an influence on antiepileptic drugs which are substrates for the enzyme. This influence may negatively affect seizure control of epilepsy patient. We present a patient whose seizures were induced by Artemisia annua, despite he was taking levetiracetam which is not a substrate for the hepatic enzyme. Therefore there would be another mechanism of seizure induction of Artemisia annua besides hepatic metabolism.


Assuntos
Humanos , Anticonvulsivantes , Artemisia , Artemisia annua , Sistema Enzimático do Citocromo P-450 , Epilepsia , Metabolismo , Convulsões
3.
Artigo em Coreano | WPRIM | ID: wpr-67441

RESUMO

Amyloidosis is a systemic disorder associated with clonal plasma cell dyscrasia. Nephrotic syndrome, congestive heart failure, autonomic and peripheral neuropathy is often associated features in amyloidosis. Early diagnosis is most important because of different prognosis by stage. The diagnosis can be delayed since symptoms of amyloidosis may vary or nonspecific. We describe a patient of myeloma-associated amyloidosis, who showed orthostatic intolerance as the first symptom of the disease.


Assuntos
Humanos , Amiloidose , Diagnóstico , Diagnóstico Precoce , Insuficiência Cardíaca , Síndrome Nefrótica , Intolerância Ortostática , Paraproteinemias , Doenças do Sistema Nervoso Periférico , Prognóstico
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