Research advances on the promotive healing effect of hydrogel dressing for diabetic foot wound / 中华烧伤杂志

In recent years, the number of diabetic patients has gradually increased, and the number of patients with diabetic foot has also increased. Diabetic foot has a high rate of disability and death, seriously affects the patients' quality of life, shortens life expectancy, and brings heavy social burden. The current treatment methods for diabetic foot are insufficient. The concepts and methods of tissue engineering provide new thoughts and means for the treatment of diabetic foot. This article introduces the pathogenesis of diabetic foot wounds, the factors leading to non-healing of diabetic foot, the applications of functional hydrogel dressings in the treatment of diabetic foot and their technical methods of functional hydrogel dressings for treating skin wounds in diabetic animals, and the future development direction of functional hydrogel dressing for treating diabetic foot wounds is prospected.

Three-dimensional finite element simulation of surgical correction for Lenke 2 type adolescent idiopathic scoliosis / 第二军医大学学报

Objective To simulate different anterior and posterior correction strategies using finite element model of Lenke 2 type adolescent idiopathic scoliosis (AIS), in an effort to seek the optimal surgical protocol. Methods The finite element model of Lenke 2 type AIS was established and used to simulate five surgical strategies. The effectiveness and shoulder balance parameters were compared among different surgical approaches. Results The coronary proximal thoracic (PT) Cobb angle and corrective rates of the five surgical strategies were 21. 5(44. 8%), 26. 5(32. 1%), 28. 1(27. 9%), 34. 1(12. 5%), and 32(17. 9%). The corrective rates for the main thoracic curves were not significantly different among the five strategies, and the physiological sagittal configuration was maintained. Postoperative radiographic shoulder balance parameters were increased for all five surgical protocols. Except for strategy A (posterior fusion from T2 to Tn), other four strategy achieved the following outcomes: coracoid height differences* 9 mm, clavical angle>2. 5° and clavicular tilt angle differences* 4. 5°. Conclusion Simulation of posterior correction and fusion to T2 including both thoracic curve can achieve excellent three-dimensional corrective results and balanced shoulders for Lenke 2 type AIS model with preoperative left elevated shoulder. Partial fusion of PT curves to T3 or T4 results in inferior corrective rate of PT curve and mild or moderate shoulder imbalance. Simulation of anterior or posterior selective main thoracic curve fusion has very low spontaneous PT corrective rate and can lead to deteriorated shoulder imbalance slight to moderate degrees.