RESUMO
Abstract: Suxamethonium chloride is a depolarizing muscle relaxant used in general anesthesia. In overdose, it causes adverse reactions such as bradycardia, arrhythmia, cardiac arrest, and death. The article reviews the progress on testing methods of suxamethonium chloride such as infrared spectroscopy, chemical color reaction, chemical titration, enzyme electrode, chromatography and mass spectrometry.
Assuntos
Humanos , Anestesia Geral , Arritmias Cardíacas/induzido quimicamente , Técnicas Biossensoriais , Bradicardia/induzido quimicamente , Cromatografia , Overdose de Drogas , Parada Cardíaca/induzido quimicamente , Espectrometria de Massas , Fármacos Neuromusculares Despolarizantes/análise , Espectrofotometria Infravermelho , Succinilcolina/análiseRESUMO
OBJECTIVE@#Based on a retrospective analysis of the drunk driving cases, to explore the drunk drivers' personnel composition, occurrence time and psychology.@*METHODS@#As a result of punishment of the drunk driving by criminal law for one year from May 1st, 2011 to April 30th, 2012, 91 drunk driving cases were statistically analyzed the easy-happening time of drunk driving, the drunk drivers' age, gender, occupational characteristics, domicile and psychological factors.@*RESULTS@#In 97 drunk driving cases, 26-40 years old, non-local domiciled and non-professional male drivers were prone to drunk driving at night from 22:00 to 5:00.@*CONCLUSION@#The behavior of drunk driving is relevant to time, age, genders and occupation. The psychological characteristics of most drivers are fluky, making-life-easy, competitive and peacockish.
Assuntos
Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Acidentes de Trânsito/estatística & dados numéricos , Distribuição por Idade , Consumo de Bebidas Alcoólicas , Intoxicação Alcoólica/psicologia , Condução de Veículo/psicologia , China/epidemiologia , Medicina Legal , Fatores de Risco , Distribuição por Sexo , Comportamento Social , Fatores de TempoRESUMO
Micellar liquid chromatography (MLC) is a reversed phase liquid chromatography with mobile phases containing surfactant above its critical micellar concentration (CMC). The basic mechanism and advantages of MLC in physicochemical analysis were reviewed, and its applications in analysis of drugs, barbiturates, benzodiazepines were chiefly introduced in this paper. MLC is a potential method to toxicological analysis due to strong selectivity, wide application scope and easy biological samples, etc.