RESUMO
Objective: To investigate the value of enhanced CT combined with histogram analysis in differential diagnosis of Warthin tumor and pleomorphic adenoma(PA) of parotid. Methods: Maxillofacial plain and enhanced CT were performed on 37 patients with Warthin tumor (Warthin tumor group) and 28 patients with PA (PA group). CT values of plain, arterial phase (AP) and venous phase (VP) CT of lesions were measured, and the enhanced patterns and pure enhanced values were recorded. Then the parameters of histogram analysis, including the mean, standard deviation (StdDev), minimum (Min), maximum (Max), Median, skewness (Skew) and kurtosis (Kurt) were calculated. The differences of all parameters were compared between groups. ROC curves of parameters being statistically different between groups were drawn for differential diagnosis of Warthin tumor and PA of parotid gland, and the corresponding diagnostic efficacy were analyzed. Results: There were statistically differences of CT values in each phase, AP pure enhanced values and enhanced patterns between groups (all P<0.05), and MeanAP, MinAP, MaxAP, MedianAP, SkewAP, MeanVP, StdDevVP, MinVP, MedianVP and SkewVP also showed significant differences (all P<0.05). AUC and Youden indexes of enhanced pattern, AP pure enhanced value, MeanAP, MinAP, MaxAP, MedianAP and SkewAP were all higher than those of VP histogram parameters in differential diagnosis of PA and Warthin tumor. SkewAP had the highest Youden index (0.71), with AUC of 0.88. The diagnostic efficacy enhanced pattern+SkewAP was the most effective, with AUC, Youden index, sensitivity and specificity of 0.94, 0.80, 83.58% and 96.43%, respectively. Conclusion: Enhanced CT combined with histogram analysis based on AP images were helpful to differential diagnosis of Warthin tumor and polymorphic adenoma of parotid. The diagnosis performance of combined parameters was better than that of single parameter.
RESUMO
Objective To investigate the clinical diagnostic values of quantitative DTI and MRS in AIDS-related cerebral tuberculosis. Methods 17 cases confirmed with AIDS and brain tuberculosis,16 volunteers were recruited to perform routine MRI,DTI and MRS sequences. Morphological characteristics of lesions were observed.ADC,FA,rADC,rFA,NAA/Cho,NAA/Cr and Cho/Cr of the lesions solid areas,edematous areas,normal areas and contralateral corresponding normal areas were measured and their variances in different areas were analyzed. Results Significant differences of the values were observed among the three regions of AIDS-related brain tuberculosis,the results of multiple comparisons between the three areas had statistical significances (P <0.05)excepted NAA/Cr between edematous and contralateral areas.ADC,FA,rADC,rFA,NAA/Cho,NAA/Cr on solid areas were lower than that on edematous areas,Cho/Cr on solid areas was higher than that on other two areas.The diagnostic efficiency of rFA value to distinguish solid and edematous areas was the highest by ROC analysis(P <0.05).The normal areas of the two groups had statistical significances(P <0.05)excepted Cho/Cr.Conclusion DTI is valuable to display the lesions micro-structure changes and MRS can reflect the early pathology metabolites changes of AIDS-related tuberculosis.