The microbiome in inflammatory bowel diseases: from pathogenesis to therapy

Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence worldwide in the 21st century while its accurate etiology remains unclear. In the past decade, gut microbiota dysbiosis has consistently been associated with IBD. Although many IBD-associated dysbiosis have not been proven to be a cause or an effect of IBD, it is often hypothesized that at least some of alteration in microbiome is protective or causative. In this article, we selectively reviewed the hypothesis supported by both association studies in human and pathogenesis studies in biological models. Specifically, we reviewed the potential protective bacterial pathways and species against IBD, as well as the potential causative bacterial pathways and species of IBD. We also reviewed the potential roles of some members of mycobiome and virome in IBD. Lastly, we covered the current status of therapeutic approaches targeting microbiome, which is a promising strategy to alleviate and cure this inflammatory disease.

A brief introduction to the cultivation of traditional Chinese medicine students based on the phenomenon of "traditional Chinese medicine experimental class" / 国际中医中药杂志

High education plays the most important part in the cultivation of TCM students at present. One of the main problems TCM facing is the professional accomplishment of TCM students cultivation underlying the modes of college education. Based on the data of "TCM Experimental Class" in universities, we analyzed the effecting factors and related prospects behind this cultivation mode as well as made a preliminary discussion on the training objectives and contents of this model combined with the history and fundamental law of TCM students training.