RESUMO
β-blocker is one of the commonly used anti-hypertensive drugs， and there are obvious differences in the selection of this class of drugs. Nebivolol is a third-generation β-blocker with a unique mechanism of action. This article summarizes the clinical application of nebivolol in anti-hypertensive treatment in recent years， and it is found that compared with other β-blockers， nebivolol has certain clinical treatment advantages. In addition to having a significant antihypertensive effect， it also has little impact on sexual function and heart rate of patients， and does not affect the blood glucose and lipid metabolism， so the drug is more suitable for some special groups of patients， including sexually active male hypertensive patients， hypertensive patients with complications such as type 2 diabetes mellitus and metabolic syndrome.
RESUMO
OBJECTIVE: To compare TLC fingerprints between different batches of compound Herba taraxaci enemas (CHTE) ant to lay a foundation for establishing a more stable preparation technics and quality standards for CHTE. METHODS: The chloroform extract of 2 batches of CHTE were chromatographed by TLC and the samples were scanned by TLC scanner at a single wavelength of 280nm,the difference between different batches was compared. RESULTS: The TLC of chloroform extracts was well-separated,there were 6 common peaks and 2 non-common peaks in the TLC of 2 batches of samples, with some of the peaks identified in terms of the medicinal material categories, but there was a significant difference in contents among the common peaks. CONCLUSIONS: It was hard to guarantee the relative conformity in numbers of components and the contents between different batches of preparations,the preparation technics and quality standard of raw materials remain to be further optimized and the quality standard for Chinese herb medicinal preparations in hospital should be improved further.