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Objective To compare HC video-laryngoscope with Macintosh laryngoscope for tracheal intubation.Methods Sixty ASA Ⅰ or Ⅱ patients of both sexes,aged 18-64 yr,with body mass index 19-27 kg/m2,Mallampati grade Ⅰ-Ⅱ,undergoing elective surgery,were randomly divided into 2 groups (n =30 each):HC video-laryngoscope group (group H) and Macintosh laryngoscope (group M).After induction of anesthesia,the patients underwent orotracheal intubation assisted by HC video-laryngoscope in group H,and by Macintosh laryngoscope in group M.The glottic exposure time,intubation time,Cormack-Lehane grade,the number of pressing the cricoid and intubation-related complications were recorded.Results The rate of satisfactory glottic exposure was significantly higher and the number of pressing the cricoid was smaller in group H than in group M (P ＜ 0.05).There was no significant difference in the glottic exposure time,intubation time and incidence of intubation-related complications between the two groups (P ＞ 0.05).Conclusion The efficacy of tracheal intubation guided by HC video-laryngoscope is better than that guided by Macintosh laryngoscope.
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ObjectiveTo compare the neuromuscular blockade induced by different target effect-site concentrations (Ces) of rocuronium in female patients.MethodsOne hundred and twenty ASA Ⅰ or Ⅱ female patients,aged 40-55 yr,with body mass index 18-22 kg/m2,scheduled for elective thyroid or breast surgery under general anesthesia,were included in the study.Anesthesia was induced with midazolam 0.1 mg/kg and fentanyl 5 μg/kg.Target-controlled infusion of rocuronium was started to facilitate tracheal intubation as soon as the patients lost consciousness.The patients were randomly divided into 4 groups ( n =30 each):A,B,C and D groups.In groups A,B,and C,the target Ce of rocuronium was set at 3.5 μg/ml during induction of anesthesia and at 1.0,1.2 and 1.4 μg/ml respectively during maintenance of anesthesia.In group D,the target Ce of rocuronium was set at 3.8 μg/ml during induction of anesthesia and at 1.2 μg/ml during maintenance of anesthesia.The onset time (time from the beginning of target-controlled infusion of rocuronium to T1 =5％ of the control twitch),recovery time (when T1 retumed to 25 ％ of the control twitch),recovery index (the time for Tt to return from 25 ％ to 75 ％of the control twitch),and the total amount of rocuronium consumed during operation were recorded.The intubation conditions and degree of muscle relaxation during operation were assessed.ResultsNeuromuscular block during operation was significantly better and the rate of satisfactory neuromuscular block was significantly higher in groups B,C and D than in group A ( P ＜ 0.05).Onset time was significantly shorter in group D than in groups A,B and C ( P ＜ 0.05).Compared with group C,the total amount of rocuronium consumed during operation,recovery time and recovery index were significantly decreased in groups A,B and D ( P ＜ 0.05).There was no significant difference in the total amount of rocuronium consumed during operation,recovery time and recovery index between groups B and D (P ＞0.05).ConclusionRocuronium with the target Ce set at 3.8 and 1.2 μg/ml during induction of anesthesia and mainterance of anesthesia respectively can provide satisfactory neuromuscular block,is helpful to the recovery of neuromuscular block and is more suitable for female patients.