Optimization of bacterial cellulose fermentation medium and observation of bacterial cellulose ultra-micro-structure / 生物工程学报

In order to improve the yield of bacterial cellulose (BC), the fermentation medium of BC-producing strain J2 (Gluconobacter) was optimized, and BC ultra-micro-structure was observed. Initially, Plackett-Burman design was employed to evaluate eight variables which were relevant to BC production. Three statistically significant parameters including yeast extract, ZnSO4, ethanol were selected and other 5 variables were not significant (P > 0.05). The optimized levels of three variables were defined by Box-Behnken design and response surface methodology (RSM). BC ultra-micro-structure was observed by scanning electron microscope (SEM) with cotton cellulose as comparison. The results indicated that the BC yield under the optimum fermentation medium was 11.52 g/100 mL, which was as 1.35 times as that under the original fermentation medium. The SEM photos manifested that bacterial cellulose ribbon, with a diameter less than 0.1 microm, was less than cotton cellulose ribbon. The bacteria inside the cellulose net were eliminated after the NaOH treatment.

Implications of discipline amalgamation and integration in an independent academic medical university / 中华医学教育探索杂志

Merging medical universities with comprehensive universities has become an important aspect of colleges’and universities’reform in China.However,after merging with a comprehensive university,some problems have happened: decreased management efficiency as a result of over-hierarchical administration,neglect of own features of medical faculties,as well as less than expected cooperation of medical and nonmedical subjects and so on.In this context,from the perspective of an independent medical university,a theoretical and practical model for developing multidisciplinary faculty was formulated and implemented in an academic medical university,including background analysis,feasibility,developing principles,integrating strategies,in the hope of providing some implications for other independent medical schools.

Problems in Degree-oriented Education in Clinical Medicine and Solutions / 中华医学教育探索杂志

In spite of the relative success achieved in degree-oriented education program in clinical medicine during its preliminary trial stage, problems remain in regard to its recognition and understanding, administration policy, testing systems and the quality control. To further improve the Effects of the actual teaching, it is of high importance that we further our understanding, strengthen the administration, consolidate the testing system and implement better supervision of the teaching procedures of the program.