Development of a digital cardiac pacemaker for animals and its application in medical research / 生物医学工程学杂志

In this research and development project, we used the general microprocessor as a core to constitute the animal cardiac pacemaker in vitro. Control of the pacemaker's settings was carried out by transmitting parameters through a serial communication interface. Finally, our pacemaker reaches a satisfying test result in activating the cardiac outer membrane of the rabbits. Full digital pacemaker has high precision, good stability, and has an intuitive way to set parameters. Owing to its smaller size, lower cost, and easier mass production, the digital pacemaker is a good candidate to replace costly medical pacemakers for activating the animal's heart.

The design of an instrument furnished with hydrogen clearance technique for measuring local blood-flow and the microcomputer analysis curve on hydrogen clearance / 生物医学工程学杂志

A new instrument, furnished with hydrogen clearance technique for measuring local blood-flow, was designed by use of new electronic components and a microcontroller. The corresponding program was developed. The curve of hydrogen clearance was sampled automatically by microcomputer, fitted into an exponential function by least square method, and then the local blood-flow was calculated. The cerebral blood-flow in the rat's striatum had been measured using the system. The fitted curve corresponds with the curve of hydrogen clearance and the obtained parameter was correct. The design of the instrument was reasonable. It can work reliably and stably. The calculated results are more accurate and they can be acquired more quickly, because the curve of hydrogen clearance is automatically sampled and analyzed by the microcomputer.