Autoantibodies and inflammatory cytokines in children with systemic-onset juvenile idiopathic arthritis / 国际检验医学杂志

Objective To investigate the changes of autoantibodies and inflammatory cytokines in children with system‐onset ju‐venile idiopathic arthritis (So‐JIA) .Methods Serum concentrations of autoantibodies and inflammatory cytokines were measured in children with So‐JIA at active phase or remission phase by using indirect immunofluorescence method and enzyme‐linked immu‐nosorbent assay .Healthy children were enrolled as control group .Results The assay positivity of antikeratin antibody (AKA) and anti‐cyclic citrullinated peptide antibody (anti‐CCP) was 29 .4% and 47 .1% in active phase group ,and was 17 .2% and 27 .6% in remission group .The differences between the two groups were significant (P0 .05) .Conclusion AKA and anti‐CCP might be with high diagnostic specificity to So‐JIA ,but the sensitivity could be low ,and combined detection could increase the diagnostic positivity .Inflammatory cytokines ,such as IL‐6 and IL‐17 ,might be associated with the activity of So‐JIA ,which could be important biomarkers of So‐JIA .

Treating Displaced Patellar Fracture with Longitudinal Incision ＆ Internal Fixation of the Sidelong Anterior Tension-band Wiring / 中国现代医生

Objective To explore the clinic effects of treating the displaced patellar fracture with a small longitudinal midline incision and internal fixation of the sidelong figure-of-eight anterior tension-band wiring. Methods 93 ea.ses of the displaced patellar fractures were internal fixated with the sidelong figure-of-eight anterior tension-band wiring(1.2 mm) simply, which made a longitudinal midline incision,it length can be made equal to the diam of patella approximately,that gives to enough expose the entire anterior surface of the patella and the patellar tendons. Results Follow-up for 6 to 30 months,93 cases were all obtained bony union. By Zhang Chun-cai score,there were 67 cases excellent,23 good and 3 fair,the excellent and good rate was 96.8%. Conclusion Treating patellar fracture with the fixation methods are very stabilization,and can functional exercise in early. It had similar results to reports using modified (with Kirschner wires) tension band techniques. The methods is simple and mini-trauma and invasive device minimally which results in fewer complications,especially as fractures traversed and comminuted with relative larger fragments are concerned.