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Objective To improve the treatment of hypertensive basal ganglia hemorrhage choosing 3 different surgical methods.Methods 120 patients with hypertensive basal ganglia hemorrhage were retrospectively analyzed,including 28 cases treated by normal micro-craniotomy,62 cases by micro-craniotomy with small window of bone,and 30 cases by endoscopic surgery.Results During three months of follow-up,15 patients died and 105 patients survived.Of survival patients,2 patients presented plant survival status,64 patients moderately or severely disabled,while 39 patients recovered.The disability rate after endoscopic surgery was lower than the other two.Conclusions Selecting appropriate surgical methods could save most of patients with hypertensive basal ganglia hemorrhage and endoscopic surgery was conducive to reduce the disability rate.
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AIM: To investigate the expression and the significance of β-catenin and Cyclin D1 in gliomas. METHODS: The SABC immunohistochemistry were used to detect the expression of β-catenin and Cyclin D1 in 49 brain gliomas and 5 normal brain tissues. RESULTS: The β-catenin positive ratio in normal brain tissues and glioma samples are 2/5 and 38/49(P<0.01) respectively, and the Cyclin D1 positive ratio in normal brain tissues and gliomas are 1/5 and 42/49(P<0.01); Compared with the normal brain tissue, both the immunohistochemical expression of β-catenin and Cyclin D1 were up-regulated(P<0.05), and the expression of β-catenin and Cyclin D1 between the normal brain tissues and gliomas exhibited significantly difference (P<0.01). CONCLUSION: β-catenin and Cyclin D1 increased in gliomas may be precipitate the tumorigenesis of glioma.