Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
1.
Chinese Journal of Surgery ; (12): 285-287, 2004.
Artigo em Chinês | WPRIM | ID: wpr-311128

RESUMO

<p><b>OBJECTIVE</b>To explore multi-drug resistance (MDR) of bladder cancer for the intravesical instillation.</p><p><b>METHODS</b>Using immunohistochemical staining, in 44-case human bladder cancer cells, the expressions of P-glycoprotein (P-gp), glutathione S-transferase (GST-pi) and topoisomerase (TOPO-II), were detected to find out the resistance to drugs.</p><p><b>RESULTS</b>P-gp had a higher expression in 54.5% cases. GST-pi had no or a lower expression in 65.9% cases. TOPO-II had a higher expression in 29.5% but a lower expression in 65.9% cases.</p><p><b>CONCLUSION</b>Detecting the factors of MDR in bladder cancer cells could help to choose drugs for intravesical chemotherapy.</p>


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Membro 1 da Subfamília B de Cassetes de Ligação de ATP , Administração Intravesical , DNA Topoisomerases Tipo II , Resistência a Múltiplos Medicamentos , Resistencia a Medicamentos Antineoplásicos , Glutationa Transferase , Imuno-Histoquímica , Neoplasias da Bexiga Urinária , Tratamento Farmacológico , Metabolismo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA