Therapeutic Observation of Acupuncture-moxibustion for Chronic Simple Rhinitis Due to Yang Deficiency / 上海针灸杂志

Objective To observe the clinical efficacy of XIE’s Wen Du Qu Mai (Warming the Governor Vessel to expel smog) needling method plus heat-sensitive moxibustion in treating chronic simple rhinitis due to yang deficiency. Method Eighty patients with chronic simple rhinitis due to yang deficiency were randomized into a treatment group and a control group, 40 in each group. The treatment group was intervened by acupuncture plus heat-sensitive moxibustion, while the control group was by medication. The symptom and sign score was observed before and after 1-week treatment, and the clinical efficacy was compared. Result The total effective rate was 85.0%in the treatment group versus 55.0% in the control group, and the difference was statistically significant (P<0.05). The symptom and sign scores were changed significantly after treatment in both groups (P<0.01,P<0.05). After treatment, the symptom and sign score in the treatment group was significantly different from that in the control group (P<0.05). Conclusion XIE’s Wen Du Qu Mai needling method is effective in treating chronic simple rhinitis due to yang deficiency.

Preparation and in vitro evaluation of a new terbinafine hydrochloride bioadhesive film-forming gel / 中国药科大学学报

@#The aim of this study was to conduct the preparation and pharmaceutical characterization of a new type of terbinafine hydrochloride bioadhesive film-forming gel. The viscosity of the gel of(13 299±51)mPa ·s, pH of 3. 50±0. 50, and the shearing viscosity of(196±4)g/cm2 was found. This new gel turned out to be a layer of solid film on the application site in a very short time. The remaining solid ratio of the resulting film was estimated to be(50. 74±2. 81)%; the tensile strength was(1. 17±0. 21)MPa; and the breaking elongation was(21. 42±3. 24)%. In vitro release behavior of terbinafine hydrochloride from the film was investigated according to the paddle over disk method in ChP2010. Terbinafine hydrochloride released continuously for 10 h from the film. Improved Franz type diffusion cells were used in vitro transdermal studies by the application of excised minipigs skins. No penetration of drug into the receptor medium across the skin existed and so it could imply the safety for local application. It was found that(93. 05±5. 66)% of drug stayed on the skin surface while(1. 15±0. 85)% entered into the skin, which was beneficial for the treatment of superficial skin fungal infection.

The laboratorial study of liver tissue photocoagulation using semiconductor laser / 中华放射学杂志

Objective To evaluate the size of the liver tissue necrosis at different power and energy, to search the size of liver tissue necrosis at ideal power and energy, and to provide dependable data for semiconductor laser-therapy in malignant hepatic tumor. Methods Ten rabbits were included, and the rabbit liver tissue was fired using semiconductor laser at 1 W, 2 W, and 3 W with the energy of 200 J, 400 J, 600 J, 800 J, and 1 000 J. The diameters of the necrosis and charring in the target area were measured. Results The diameter of the liver tissue necrosis and charring was from 4.3 mm and 7.8 mm at 1 W to 10.4 mm and 21.9 mm at 2 W in 1 000 J. From 2 W to 3 W, the diameter of the liver tissue necrosis and charring remained unchanged. At the power of 2 W, the diameter of liver tissue necrosis and charring was proportional to the energy, and the areas of necrosis were correlated with that of charring. Conclusion Semiconductor laser photocoagulation is safe and feasible. This experiment supplies valuable laboratorial data for further clinical study.

Diagnostic value of the digital subtraction angiography in moyamoya disease / 介入放射学杂志

Objective To evaluate the value of DSA in the diagnosis of staging moyamoya disease (MMD).Methods DSA of 31 patients with MMD were reviewed retrospectively. Results The stenosis or occlusion with different extents of the supracranial internal carotid arteries and the collateral circulations were shown in DSA of the all patients. MMD lesions of 57 cerebral hemispheres shown in the DSA of 31 patients were diagnosed by staging according to the description of Suzuki: Stage Ⅰ in 4 cerebral hemispheres; Ⅱ,10;Ⅲ17;Ⅳ12;Ⅴ6 and Ⅵ,8. Conclusions DSA could show clearly the stenotic degree, occlusive site and collateral circulation of the MMD and simultaneously with the staging of the disease; and thus guiding the choice for early surgical teatment.