Study on quality standards of decoction pieces of salt Alpinia / 中国中药杂志

<p><b>OBJECTIVE</b>To establish the quality criteria for decoction pieces of salt Alpinia.</p><p><b>METHOD</b>Decoction pieces of salt Alpinia were measured with moisture, total ash, acid-insoluble ash, water-extract and volatile oils according to the procedures recorded in the Chinese Pharmacopoeia 2010. The content of Nootkatone was determined by HPLC, and NaCl, by chloridion electrode method.</p><p><b>RESULT</b>We obtained results of total ash, acid-insoluble ash, water-extract and volatile oils of 10 batches of decoction pieces of salt Alpinia moisture; Meanwhile we set the HPLC and chloridion electrode method.</p><p><b>CONCLUSION</b>This research established a fine quality standard for decoction pieces of salt Alpinia.</p>

Swelling property of common hydrophilic polymers and their use in push-pull osmotic-pump tablets / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate the feasibility of swelling hydrogel instead of polyethylene oxide as swelling polymer in push-layer of push-pull osmotically controlled-release tablets.</p><p><b>METHOD</b>The swelling patterns of tablets made of pure polymers were studied by immerging the tablets into purified water and testing their size at different time points. The push-pull osmotic-pump tablets were prepared and their release patterns in vitro were studied and compared by their similar factor (f2).</p><p><b>RESULT</b>Tablets with different swelling materials all showed satisfying release pattern in vitro and their release ratio at 12 h were all above 80%.</p><p><b>CONCLUSION</b>With its release rate and cumulative release percentage at 12 h, the mixture of HPMC K15M and CMCNa in ratio of 1:1 is the best choice instead of polyethylene oxide as swelling polymer in push-layer.</p>

Study on adsorptive properties of spherical activated carbon on several kinds of active ingredient from Chinese materia medica / 中草药

ObjectTo study the adsorptive properties of spherical activated carbon on some effective ingredients from Chinese materia medica (CMM) and to approach the application feasibility to CMM purification. Methods The spherical activated carbon with high strength has been successfully prepared by the carbonation and activation of polymeric resin. The apparent and theoretical adsorption capacities under the condition of static operation were investigated by Langmuir monolayer adsorption model. Elution by 75% alcohol was studied. Results The static adsorption capacities of the berberine hydrochloride and dioscin were 35.46 mg/g and 47.12 mg/g, and theoretical adsorption capacities were 96.16 mg/g and 102.04 mg/g, respectively. The apparent adsorption amount of rutin was 40.88% mg/g. The elution ratio were 83.71%, 91.45%, and 87.69%, respectively. Conclusion The spherical activated carbon adsorbent shows better comprehensive adsorption properties and can be used to purification.