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Objective To investigate the expression of VEGF-C,CD31 and MVD,in human ovarian epithelial carcinoma tissues,development and metastasis of epithelial ovarian carcinoma by observing their expression and analyzing their correlation.Methods 40 samples of ovarian epithelial carcinoma tissues and 20 samples normal ovary tissues were selected from 2004 to 2005 in the third affiliated hospital of Harbin Medical University,as well as 20 cases of normal ovarian tissues samples as control using immunohisrochemical staining assay,we analyzed the expression of VEGF-C,MVD detected by CD31.The relationship of these three factors with patients age tumor stage,differentiation,pathohistological type,were analyzed.Results 67.5%(27/40)had high expression of VEGF-C,15%(3/14)had low espression.The survival of patients with high VEGF-C expression was significantly worse than that of patients with low and negative expression.Conclusion VEGF-C and CD31 may play an important role in the occurrence and development of epithelial ovarian tumors,while MVD maybe associated with the ivasion and metastasis of carcinoma.The detection of VEGF-C combined with CD31 and MVD can objectively reflect the biological behavior of epithelial ovarian tumor.
RESUMO
Objective To investigate the clinical value of different treatments of uterine artery and vein in laparoscopic hysterectomy. Methods In 184 patients accepting lapaxoscopie hysterectomy, ligasttre vessel sealing system ,was applied to uterine vessels, while bipolar electric coagulation to coagulate the uterine vessels during the operation. Results Among the groups, women undergoing ligasure hand the smaller amount of estimated blood loss and was associated with shorter operating time, there were statistically significant differences among the two groups( P＜0.01). Conclusion Each of the two operative ways is feasible or laparoacopic hysterectomy. The way of dissociating uteri arteriovenous completely before they were cut off with ligasure in laparoscopic panhysterectomy has many important clinical value such as easy appliance, safety, convenient operation, clear operation field and so on.