Correspondence between neural process and frontal lobe gyri on coronal sections / 局解手术学杂志

Objective To explore the corresponding rules between neural process and frontal lobe gyri and provide anatomic basis for locating frontal lobe gyri by neural process. Methods 20 normal cadaver heads were transected into brain slices with thickness of 6 mm after dyeing frontal lobe gyri. Typical planes were observed,while the correspondence between neural process and frontal lobe gyri on coronal sec-tions were analyzed and summarized. Results There was 1 or 2 processes for almost frontal lobe gyri,with the direction of neural process in different coronal sections being unchanged and symmetric. Conclusions The corresponding rules between neural processes and frontal lobe gyri may be obtained and the frontal lobe gyri on coronal sections may be located through neural processes.

Animal models of intervertebral disc degeneration: economy, feasibility, reliability and controllability / 中国组织工程研究

BACKGROUND: Animal models are critical to study the mechanism, prevention and treatment of intervertebral disc degeneration (IDD). Therefore, constructing an ideal animal model of IDD is the key to further study IDD. OBJECTIVE: To review the selection and construction methods of the IDD model, so as to select and construct an ideal animal model of IDD. METHODS: A retrieval of CNKI, WanFang, VIP, SinoMed and PubMed databases was performed for the articles published before December 2016. The keywords were "intervertebral disc degeneration, animal model" in English and Chinese, respectively. All the articles were selected from the authoritative magazines, and finally 56 eligible articles were included. RESULTS AND CONCLUSION: There are many kinds of animals used for constructing the IDD model, including small and large animals. The former has a small volume of intervertebral disc that is beneficial for nutrient and metabolite transport,so it can be used for long-term in vitro culture.The latter has a large volume of intervertebral disc,which is appropriate for biomechanical study.The animal models of IDD include in vivo and in vitro models:the in vivo models include the changed biomechanics,destroyed physical structure,spontaneous and systemic disease models;the in vitro models include in vitro cellular and organ models.However,there is still a lack of an ideal animal model that can fully simulate human IDD. Noticeably, similarity, comparability, economy, feasibility, reliability and controllability should be considered.