Laparoscopic cholecystectomy with or without percutaneous transhepatic gallbladder drainage for acute severe cholecystitis: a meta-analysis / 中华肝胆外科杂志

Objective@#To compare laparoscopic cholecystectomy (LC) with or without percutaneous transhepatic gallbladder drainage (PTGD) for acute severe cholecystitis.@*Methods@#According to the predefined inclusion and exclusion criteria, 23 articles were selected for this meta-analysis. All patients were treated with LC with or without PTGD. A meta-analysis was used to analyze the clinical efficacy.@*Results@#Compared with LC, all the surgical indicators of LC with PTGD were significantly better than LC alone (all P≤0.05), including the operation time: 95%CI(-27.24, -9.27); intraoperative blood loss: 95%CI(-50.25, -40.19); postoperative hospital stay: 95%CI(-3.63, -0.64); rates of conversion to open abdomen: OR=0.48, 95%CI(0.32, 0.74); rates of incision infection: OR=0.49, 95%CI(0.25, 0.99); drainage tube indwelling time: 95%CI(-2.07, -1.19); gastrointestinal function recovery time: 95%CI(-1.73, -0.77); rates of bile leakage: OR=0.23, 95%CI(0.12, 0.44); and rates of complications: OR=0.36, 95%CI(0.27, 0.48).@*Conclusion@#Compared with LC alone, PTGD+ LC is the preferred treatment for acute severe cholecystitis.

Laparoscopic cholecystectomy with or without percutaneous transhepatic gallbladder drainage for acute severe cholecystitis:a meta-analysis / 中华肝胆外科杂志

0bjective To compare laparoscopic cholecystectomy(LC)with or without percutane-ous transhepatic gallbladder drainage(PTGD)for acute severe ch01ecystitis.Methods According to the predefined inclusion and exclusion criteria.23 articles were selected for this meta.analysis.A1l patients were treated with LC with or without PTGD.A meta-analysis was used to analyze the clinical efficacy.Results Compared with LC.a11 the surgical indicators of LC with PIGD were significantly better than LC alone(all P≤0.05),including the operation time:95％CI(-27.24,-9.27);intraoperative blood loss:95％CI(-50.25,-40.19);postoperative hospital stay:95％CI(-3.63,-O.64);rates of conversion to open abdomen:OR=0.48,95％CI(0.32.0.74);rates of incision infection:OR=0.49,95％CI(0.25,O.99);drainage tube indwelling time:95％CI(-2.07,-1.19);gastrointestinal function recovery time:95％CI(-1.73,-0.77);rates of bile leakage:OR=0.23,95％CI(0.12,0.44);and rates of compli-cations:OR=0.36.95％CI(0.27,0.48).Conclusion Compared with LC alone,PTGD+LC is the preferred treatment for acute severe cholecystitis.