Global research hotspots on oncology-bibliometric analysis based on the ESI hot papers / 生物医学工程学杂志

With the increasing global burden of various cancer, an abundance of papers emerged every year in the research hotspots of oncology, covering a wide range of research types and topics. In order to facilitate interested readers to quickly grasp the frontier and hotspots of cancer research, it would be helpful to sort out and summarize the research topic in a timely manner. According to the classification of disciplines, we screened the Essential Science Indicators (ESI) hot papers released in 2019 for the ones in the oncology field, utilized methods such as bibliometrics, statistical description, hierarchical induction, analysis and interpretation to further reveal the context and characteristics of research in the field of oncology, summarized the latest progresses and future directions in the field, and provided information and hints for the trajectory of future research. A total of 549 papers were included, which were mainly from the field of clinical medicine; the country with the most publications was the United States, while China ranked the fourth in terms of contribution; the research institution with the highest number of published papers was University of Texas system;

Research progress of the relationship between 14-3-3ζ and malignant tumor / 实用肿瘤学杂志

The 14-3-3 protein is a highly conserved acidic polypeptide family involved in intracellular signaling,protein transportation, cell proliferation, invasion, migration, and apoptosis. Many studies have shown that 14-3-3ζhas a high expression level in many malignant tumors. This paper introduces the structure of 14-3-3ζ,the biological function,and the development of the malignant tumor ( breast cancer,lung cancer,hepatocel-lular carcinoma,glioma,head and neck neoplasms) related to the development of 14-3-3ζand treatment of ma-lignant tumor in order to provide valuable information and ideas.

Advances in studies on intestinal absorption kinetics of phenolic glycosides / 中国生化药物杂志

This review analyzed domestic and foreign literatures on intestinal absorption,introduced the current methods and models commonly used in phenolic glycosides researches and their impacts focused on intestinal absorption,summarized the research status,aims to provide a reference for improving their oral bioavailability,improve formulations,new medicine and clinical rational use of phenolic glycosides.