RESUMO
One new sesquiterpene was isolated from the fermentation broth of Streptomyces sp. and the structure was elucidated by spectral analysis as caryolane-1, 6beta-diol (1). An intermediate 1alpha, 6beta, 11-eudesmanetriol (2) in the biosynthesis of geosmin was also found in this strain which proved sequence for the reactions, especially bicyclization preceding dealkylation.
RESUMO
<p><b>OBJECTIVE</b>To investigate the constituents from Huperzia serrata.</p><p><b>METHOD</b>Two diterpenoid compounds were isolated by column chromatography with silica gel and Sephadex LH-20. The structures were elucidated by spectral analysis and X-ray crystallographic analysis.</p><p><b>RESULT</b>Their structures were determined as (15R)-12, 16-epoxy-11, 14-dihydroxy-8, 11, 13-abietatrien-7-one (1) and 3beta-hydroxysandaracopimaric acid (2).</p><p><b>CONCLUSION</b>Compound 1 was a new natural abietane-type diterpenoid, compound 2 was isolated from this plant for the first time.</p>
Assuntos
Cristalografia por Raios X , Diterpenos , Química , Huperzia , Química , Espectroscopia de Ressonância Magnética , Estrutura Molecular , Plantas Medicinais , Química , Espectrometria de Massas por Ionização por ElectrosprayRESUMO
Objective To investigate the chemical costituents from Drymaria diandra. Methods Compounds were separated and purified by repeated column chromatographies on macroporous resin D101,silica gel, and RP-18.Two compounds were identified by spectral analysis. Results Two compounds were isolated from D. diandra. Theirs structures were identified as 6-carboxymethy1-5,7,4'-trihydroxyflavone (Ⅰ) and l-O-β-D-glucopyranosyl-(2S,3R,4E,8E)-Z-N-(2'-hydroxypalmitoyl) octadecasphinga-4,8-dienine(soya cerebroside Ⅰ,Ⅱ). Conclusion Compound I is a new compound. Compound Ⅱ is obtained from this plant for the frist time.