RESUMO
We reported the diagnosis and treatment of one neonate with purulent meningitis caused by Streptococcus dysgalactiae subsp. equisimilis infection. The eighteen-day-old girl was admitted due to fever lasting for seven hours and was diagnosed as neonatal purulent meningitis based on laboratory tests, including the routine blood test, hypersensitive C-reactive protein, procalcitonin, cerebrospinal fluid examination, and blood culture. The patient recovered and was discharged after a four-week comprehensive treatment, including antibiotics, sedatives, lowering intracranial pressure and rehydration and fluid replacement. During the follow-up of one month after discharge, the girl showed normal growth and development without any abnormality in cranial MRI or hearing. This case suggested that Streptococcus dysgalactiae subsp. equisimilis infection has a quick onset with serious conditions and rapid progress.