RESUMO
Objective:To explore the correlation between self-efficacy and depression in patients with hematologic malignancy, and analyze the mediating role of social support and the moderating effect of resilience.Methods:From February to June 2017, a total of 284 patients with hematologic malignancy in Jining Medical University Affiliated Hospital completed Connor-Davidson resilience scale (CD-RISC), social support rate scale (SSRS), general self-efficacy scale (GSES), self-rating depression scale (SDS). SPSS 21.0 software was used for statistical analysis, and the correlation was obtained by Pearson correlation analysis, and PROCESS v3.4 macro program was used to test the mediating and moderating effects.Results:Self-efficacy played a significant negatively predictive effect on depression in patients with hematologic malignancy( β=-0.35, t=-6.16, P<0.01). Social support partially mediated the correlation between self-efficacy and depression(the mediating effect was -0.05, accounted for 14.29%(-0.05/-0.35) of the total effect). Resilience moderated the mediating effect of social support on the correlation between self-efficacy and depression.The self-efficacy had no predictive effect on social support when the level of resilience was low and it had a significant negatively predictive effect on social support when the level of resilience was high (simple slope=-0.28, P<0.01, 95% CI=-0.39- -0.18). Conclusion:Self-efficacy has a moderating effect on depression in patients with hematologic malignancy.Self-efficacy affects depression through social support, and resilience regulates the mediating role of social support in the relationship between self-efficacy and depression.
RESUMO
Objective:To understand the quality of life in patients with hematologic malignancy, and to discuss the correlation among quality of life and social support and resilience in the patients, and to analyze the mediating effect of mental resilience.Methods:A total of 284 patients with hematologic malignancy from Affiliated Hospital of Jining Medical University completed social support rate scale(SSRS), Connor-Davidson resilience scale(CD-RISC) and European Organization for research and treatment of cancer quality of life questionnaires-core 30(EORTC QLQ-C30). SPSS 21.0 was used for descriptive statistics, single sample t-test, Pearson correlation analysis and SPSS macro program PROCESS v 3.4 was used for testing the mediating effect. Results:The general health level of quality of life in patients with hematologic malignancy(52.1±26.4)was significantly lower than the Norwegian norm(75.3)( t=-14.81, P<0.01). Social support was significantly positively correlated with resilience and quality of life( r=0.76, 0.31, P<0.01), and resilience was positively correlated with quality of life( r=0.45, P<0.01). Mental resilience played a partial mediating role between social support and quality of life, and the mediating effect accounted for 61% of the total effect. Conclusion:Mental resilience can be used as a mediating variable for social support which can affect quality of life.Improving the mental resilience and social support in patients with hematologic malignancy can effectively improve their quality of life.