RESUMO
Thalassemias is the most common inherited disease in the world. This study was designed to assess general health of patients with beta-thalassemia major in Gorgan, northern Iran. This descriptive study was performed on 163 patients with beta-thalassemia major whom referred to Thalghani hospital in Gorgan, northern Iran. Socio-Psychosocial status of patients was assessed by using general health questionnaire-28 [GHQ-28]. Socio-Psychosocial status of 44.2%, 46% and 9.8% of patients was normal, suspected and suffered from psychosocial disorders, respectively. Social dysfunction [12.9%] and depression [10.4%] were the most prevalent and anxiety was the less prevalent [4.9%] in the patients. There were significant correlations between psychosocial status and mother's ocupation [P<0.05], patients level of education [P<0.05] and history of associated diseases [P<0.05]. Social dysfunction and depression were the two major general health complications in betathalassemia patients in this region