relation between NYHA classification and cardiopulmonary exercise test in evaluating disability in workers with CHF

Evaluation of cardiac impairment is challenging since it involves an often difficult assessment of subjective complaints. We studied 25 workers with Chronic Heart Failure [CHF] to assess the degree of impairment and correlate our results with clinical findings, echocardiographic findings and resting ventilatory functions. Full medical history was taken and they were subjected to, physical examination, ECG, CBC, chest x-rays, echocardiography, resting ventilatory function tests and cardiopulmonary exercise test. This study showed that all the parameters of the resting ventilatory pulmonary function were reduced. The results of cardiopulmonary exercise tests showed lowered VO2max and oxygen pulse, more or less normal HRR and elevated VE/ VCO2 at rest and maximum exercise.Correlation coefficient between exercise parameters and both the grade of dyspnea according to NYHA classification and echocardiographic findings were not statistically significant. It is important to evaluate cardiopulmonary responses to exercise in workers with CHF besides NYHA classification and Echo grading for proper assessment of impairment and disability and follow-up of the treatment. Preoperative and postoperative cardiopulmonary exercise tests are recommended for all patients indicated for cardiac operation

interrelationship between Zinc; Copper and Iron in Lead intoxicated subjects

Inhibition of Hb biosynthesis in lead intoxicated subjects appears as a result of disorder in the interaction of Cu, Zn and Fe ions on delta-Am-inolevulinic acid dehydratase. [ALA-D]. Elevation of free serum copper and decrease of serum iron and zinc are the main cause of ALAD inhibition. Thus, it is safe to suggest that administration of Zn orally leads to replacement of cu from catalytic sites of this enzyme which is known as a zinc dependent enzyme

study of diabetes mellitus among railway workshops workers

In any industry there are many workers with non occupational diseases which require more medical supervision such as those having diabetes. The aim of this study was to investigate the relation of work and other epidemiological factors and liability to diabetes. 57 diabetic workers diagnosed [out of 1753 workers] working in railway workshops and 62 non diabetic workers were taken as a study and control groups. The study showed that the type of work plays a role in the prevalence of diabetes mellitus as 7% of professionals, 4.15% skilled workers, 1.25% semiskilled and 1.25% of unskilled workers were diabetics. Obesity and positive family history of diabetes mellitus are also important factors in relation with occurrence of diabetes mellitus