Oral health-related quality of life in patients with oral lichen planus / 华西口腔医学杂志

<p><b>OBJECTIVE</b>To investigate the oral health-related quality of life in patients with oral lichen planus (OLP) using the Chinese version of the oral health impact profile (OHIP)-14.</p><p><b>METHODS</b>51 patients with OLP were included and completed the questionnaire of OHIP-14 subsequently the REU scoring system was utilized to record the local condition and a visual analogue scale (VAS) to rate the pain they experienced. The reliability and validity were analyzed by SPSS 16.0 software.</p><p><b>RESULTS</b>The score of OHIP-14 was 21.67 +/- 9.45, Cronbach's alpha of the translated scale was 0.901. The items were divided into 5 domains by factor analysis. There was certain logical relation between the items in the same domain. There was highly significant association between the OHIP-14 score and REU score as well as VAS score (r=0.608, 0.807, P<0.000).</p><p><b>CONCLUSION</b>OHIP-14 performs well in patients with OLP, and have good validity and reliability.</p>

Analysis of clinical laboratory diagnosis in 484 Dengue fever patients / 中华检验医学杂志

Objective To analyze the characteristics of laboratory test resuits of dengue fever(DF)patients in Guangzhou area.Methods Routine tests were performed in the patients admission to hospital. Serology examination was performed in the patients in acute phase or recovery phase.The clinieal symptoms and teatures were analyzed and positive numbers and positivity ratios were calculated.Results The clinical symptoms of the dengue fever were typieal,with the features of fever,headache,myalgia and rash.The leukopenia rate was 76.0%,and the thromboeytopenia rate was 62.6%.The levels of ALT increased in 56.7%patients,and the levels of AST increased in 84.0%patients.Hypopotassemia was found in 46.1%patients.Dengue virus antibody IgM(DF-IgM)was detected positive from the first day to the 16th day of the onset,and the positive rate was 85.9% on the 8th day.Virus loads were positive by fluorescence real-time PCR in seven acute serum samples(within 3 days of the onset)of 51 cases whose DE-IgM were negative all the time, and the results was 105 -106 copies/ml(＜103 copies/ml means negative).Conclusions Clinical manifestations of this DF epidemic were typical including fever,headache,myalgia and skin rash.Most of the patients had decreased leukocyte and thrombocyte obviously.Liver damage was common but kidney damage was seldom.Halt of the patients got hypopotassemia.DF-IgM appeared in very early and persisted for a long time.The detection of DF-IgM within 7 days of the onset was helpful for diagnosis as early as possible.Viral load detected by real-time PCR could be another indicator of early pathogen diagnosis which provides complementation for antibody detection.