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Objective Treatment of type 1 diabetes mellitus has always posed a challenge to balance hyperglycemia control with hypoglycemia episodes. This review attempts to outline the application and research progress of real?time continuous glucose monitoring technology.Given the evolution of RT?CGM technologies,it is likely that today’ s more accurate RT?CGM systems will result in improved patient trust and reduced alert fa?tigue,translating into more sustained RT?CGM use,greater use of the RT?CGM data,and better outcomes.
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Objective To demonstrate the influence of PCT concentration and its descent to the prognosis of patients with hospital acquired bacterial pneumonia. Methods The PCT concentration was determined. One hundred and thirteen HAP patients were enrolled from September 2011 and November 2012 , including 64 patients in the non-survival group and 49 patients in the survival group , and 92 non-infected patients in the control group. The relationship between PCT and hospital days and survival rate was analyzed. Results The initial value of PCT in the non-survival group and in the survival group were higher than that in the control group, while the PCT in the non-survival group was the highest, with significant difference (P =0.0002). Taking PCT = 0.78 μg/L as the cut-off value, the sensitivity and specificity to predict the mortality of the HAP patients was 0.66 and 70%, respectively. A significant negative correlation was shown between PCT value and hospital days in the non-survival group. The survival rate of patients with PCT decrease over 50% was higher than that of patients with PCT decrease less than 50% after treatment. Conclusion Dynamic monitoring PCT in patients with bacterial HAP possesses a certain significance.
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Objective To investigate the relationship between serum leptin and carotid intima-media thickness in patients with type 2 diabetes mellitus. Methods 35 patients with type 2 diabetes mellitus (DM) and 16 normal controls were studied. Fasting serum leptin, fasting glucose(FBG), HbAlc, C-peptide, lipide, systolic(SBP), diastolic blood pressure(DBP), body mass index (BMI) and waist circ-umference (WC) were measured in all subjects. The intima-media thickness (IMT) of common carotid artery was measured by high-resolu-tion ultrasound imaging. Results IMT of T2DM was positively correlated with leptin concentration. Conclusion Serum leptin concentra-tion is independently associated with the IMT of carotid artery, which suggest that leptin may be an independent risk factor of atherosclerosis.
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Objective To explore the association of serum high-sensitivity C reactive protein (hs-CRP) level with leptin in patients with type 2 diabetes mellitns (T2DM). Methods 35 cases of T2DM patients were involved in the study and 16 normal subjects were taken as controls. Fasting serum leptin and CRP were measured .The relationship between them were also analyzed. Results Fasting serum hs-CRP concentration in T2DM group was higher than that in healthy control group, but serum ieptin levels is the same (P > 0.05). Partial correlation analysis demonstrated that fasting hs-CRP level was positively correlated with leptin (r =0.512 ,P =0. 018). Conclusion Fasting serum hs-CRP level is significantly raised in T2DM ,which is associated with leptin. There is chronic inflammatory reaction in T2DM patients,and leptin is possibly involved in inflammatory pathogenesis of T2DM.