The effect of independent E-buying skill training on the rehabilitation of patients with schizophrenia / 中国实用护理杂志

Objective:To explore the effect of independent E purchasing skill training on social function rehabilitation of long-term inpatients with schizophrenia.Methods:A total of 42 inpatients with schizophrenia was divided into control group (22 cases) and experimental group (20 cases) by the random number table method. The control group was treated with traditional routine nursing and drug therapy, while the experimental group was treated with independent E purchasing skills training and drug therapy. The curative effect was evaluated by the Positive and Negative Syndrome Scale (PANSS), General Self-Efficacy Scale (GSES), Scale of Social function in Psychosis Inpatients (SSPI) before the intervention and at the end of the 12th week of intervention.Results:After 12 weeks intervention, the total score of PANSS in the experimental group was (44.60 ± 5.68), of which the positive symptom was (8.50 ± 1.47), the negative symptom was (11.90 ± 2.79) and the general psychopathology was (24.05 ± 3.02). In the control group, the scores of each type were (58.95 ± 9.62), (10.36 ± 3.67), (18.00 ± 4.67) and (30.59 ± 5.13). The difference between the two groups were statistically significant ( t values were -5.810- - 2.119, P<0.05). After 12 weeks intervention, the score of GSES in experimental group was (3.45 ± 0.48) and in control group (2.29± 0.69), the difference was statistically significant ( t value was 6.256, P<0.05). After 12 weeks intervention, the total score of SSPI was (38.90 ± 2.72), the score of the subjects' ability of daily living was (10.95 ± 1.19), the mobility and communication (15.45 ± 1.57), social activity skills (12.00 ± 1.34) in the experimental group. The scores of each type were (25.32 ± 6.36), (8.36 ± 1.59), (9.95 ± 2.75) and (7.00 ± 2.56) in the control group, the differences were statistically significant ( t values were 5.918-8.513, P<0.05). Conclusions:Independent E-purchasing skills training can improve the mental symptoms of long-term inpatients with schizophrenia, improve the self-efficacy and social function of inpatients with schizophrenia, and promote the rehabilitation of social function.

Clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis / 中国生化药物杂志

Objective To observe clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis.Methods 96 patients with chronic conjunctivitis from ophthalmology department from January 2015 to October 2016 were grouped two groups by draw method,each with 48 cases.The control group was treated with ofloxacin eye drops,and observation group was treated with Zhenzhumingmu eye drops combing with ofloxacin eye drops.Related indicators are analyzed in two groups.Results ①Effective rate of observation group was 87.50%,higher than control group with 66.67%(P<0.05).②Dry eye, eye itching, eye fatigue and foreign body sensation score of observation group were (1.01±0.24),(0.93±0.22),(0.85±0.18),(0.81±0.25)points,lower than control group(1.46±0.30),(1.39±0.25),(1.16±0.21),(1.22±0.29)(all P<0.05).③Eye discomfort proportion of observation group was 12.50%, higher than control group 8.33%,but the difference was not statistically significant.Conclusion Zhenzhumingmu eye drops has exact curative effect in treatment of chronic conjunctivitis,can improve the symptoms and has high security.

The explore of the protective effect of the far-infrared radiation therapy for hemodialysis patients arteriovenous fistula function / 中国医学装备

Objective:By analyzing the principle and mechanism of far-infrared radiation therapy, explore the far infrared radiation therapy for arteriovenous fistula function protection significance. Methods: Summarized and analyzed in hemodialysis patients arteriovenous fistula dysfunction causes and hazards, combined with clinical results, analyzed the intervention and protective effect of far-infrared radiation therapy for arteriovenous fistula.Results: Long-term treatment of far-infrared radiation play a very effective role in the intervention and protection for arteriovenous fistula function maintenance.Conclusion: By analyzing the principle and mechanism of far infrared radiation therapy, summed arteriovenous fistula dysfunction reasons. Clarified the far-infrared radiation therapy has a positive clinical significance in hemodialysis patients arteriovenous fistula function of protection.

Role of Gli in Hedgehog signaling pathway and its prospect in anti-tumor therapy / 第二军医大学学报

Hedgehog (HH) signaling pathway was firstly discovered in the regulation of embryonic segments development in Drosophila; later, the biochemical and functional homologs of Drosophila HH signaling genes were also isolated in vertebrates (including human). Researchers found that HH signaling not only controls the embryonic development, but also plays an important role in tumorigenesis. Gli, a zinc finger transcription factor in the vertebral HH signaling pathway, combines to the special sequences of distal HH targeted genes and directly controls the transcription of targeted genes, playing a key role in HH signaling pathway. In this article, we summarize the role of Gli in HH signaling pathway and its prospect in cancer therapy.