Prevalence of abnormal lung function and risk factors of small airway dysfunction in asymptomatic healthy subjects receiving physical examination / 中华健康管理学杂志

Objective:To investigate the prevalence of abnormal lung ventilation function in asymptomatic subjects receiving healthy examination and the risk factors of small airway dysfunction (SAD).Methods:From August 2016 to October 2017, the pulmonary function test results of 610 healthy subjects who met the standards of this study in Fuxing Hospital affiliated to Capital Medical University were analyzed. The detection rate of abnormal lung function was described; the difference of lung function was compared between smokers and non-smokers, among groups with different smoking age, between individuals with normal body mass index and obese individuals; the risk factors of SAD was investigated; and the characteristics of abnormal lung function in asymptomatic subjects receiving physical examinations were summarized.Results:Among the 610 subjects, the overall prevalence of abnormal pulmonary function was 42.6%, and the rate of obstructive, restrictive, mixed and pure SAD were 16.7% and 5.9%, 2.5% and 17.5% respectively. The prevalence of the ratio of forced expiratory volume in 1 second (FEV 1) to forced vital capacity (FVC) (FEV 1/FVC) less than 70% was 4.6%; small airway function indicators of maximal mid expiratory flow (MMEF), forced expiratory flow at 50% and 75% of forced vital capacity (FEF 50% and FEF 75%) for smokers were significantly lower than that of non-smokers, and decreased progressively with smoking age. Smoking was an independent risk factor for SAD. Compared with non-smokers, smokers had a 65-fold increase in the risk of SAD. Obesity was not associated with SAD. Conclusions:The prevalence of abnormal lung function is high in asymptomatic subjects receiving healthy examination. The main abnormalities are obstructive ventilation dysfunction and SAD. Cigarette smoking is the major risk factor for SAD.

Clinical observation of docetaxel combined with capecitabine chemotherapy and psychological intervention after radical mastectomy for breast cancer / 中国生化药物杂志

Objective To investigate the effect of docetaxel combined capecitabine chemotherapy and psychological intervention after radical mastectomy. Methods 80 cases of radical mastectomy for breast cancer treated in our hospital from January 2015 to January 2017 were treated with docetaxel combined with capecitabine chemotherapy. According to different nursing methods, the patients were divided into 2 groups. The observation group was treated with psychological nursing, while the control group received routine nursing care. The anxiety and depression scores in two groups before and after nursing were observed and compared. Results There were no significant difference in the scores of anxiety and depression between the two groups before and after treatment. After the intervention group, patients in observation group were significantly improved, and better than the control group patients; The nursing satisfaction rate in the observation group was 97.5%,which was significantly higher than that in the control group (72.5%) (P<0.05). Conclusion After radical mastectomy of breast cancer with docetaxel combined with capecitabine chemotherapy and psychological clinical observation of dry pre found in breast cancer resection and chemotherapy as the basis, to patients with psychological intervention can improve the clinical situation of patients, promote their mental status improved, improve nursing satisfaction rate of patients, so it is worthy of reference.

The diagnostic values of Wells score and modified Geneva score for pretesting acute pulmonary embolism: a prospective study / 中华内科杂志

Objective To assess the diagnostic predictive value of Wells score and modified Geneva score for acute pulmonary embolism by prospective case series and to explore a more suitable scoring system for Chinese population.Methods All the patients suspected of pulmonary embolism (PE) and received CT pulmonary angiography (CTPA) were enrolled consecutively in Fuxing Hospital,Capital Medical University,China,from June 2009 to August 2011.Before CTPA test or on condition that test results were unknown,clinical scoring was assessed prospectively by the Wells score and the modified Geneva score.The probability of PE in each patient was assessed and the patients were divided into low,moderate and high probability groups according to the clinical scores.The result of CTPA was used as the diagnostic gold standard for PE.Diagnostic accuracy in each group was analyzed.The predictive accuracy of both scores was compared by AUCROC curve.Results A total of 139 patients met our enrollment criteria and 117 eligible patients entered our study at last.PE was diagnosed in 47 patients by CTPA with an overall prevalence of 40.2％.Prevalence of PE in the low,moderate and high pretest probability groups assessed by the Wells score and by the simplified modified Geneva score were 7.1％ (3/42),42.9％ (21/49),88.5％ (23/26)and 10.0％ (3/30),48.1％ (37/77),7/10,respectively.AUCROC curves for the Wells score and the simplified modified Geneva score were 0.872 ( 95％ CI 0.810-0.933 ) and 0.734 ( 95％ CI 0.643-0.825 )respectively,with a significant difference ( P =0.005 ).Conclusion The Wells score is more accurate for clinical predicting acute PE than the modified Geneva score.

Factors of influencing supply and utilization of rehabilitation service in five grade A hospitals in Beijing / 中国康复理论与实践

@#ObjectiveTo make sure the factors of influencing supply and utilization rehabilitation service of hospitals in Beijing.MethodsFive grade A hospitals in different districts in Beijing were surveyed to realize the condition and factors of influencing supply and utilization of rehabilitation service in polyclinics in Beijing and make sure the developing situation of departments of rehabilitation medicine, and its restriction factors in their hospitals.ResultsThe departments of rehabilitation medicine in the five hospitals had not reached to requirement of administer criterion to comprehensive hospitals, issued by Ministry of Health. The factors of influencing supply and utilization of rehabilitation service in polyclinics in Beijing included: discordant cooperation between rehabilitation section and other sections in hospitals; leaders of hospitals and clinical personnel not understanding the importance of rehabilitation early intervention much; patients and their family not understanding the special curative effect to prevent and treat disability of rehabilitation; the application for reimbursement limitation to the fee for patients to accept rehabilitation treatment and/or stay in rehabilitation section in hospitalization insurance and plan as a whole, and so on.ConclusionThe factors above limit the further development of rehabilitation service of polyclinics in Beijing. Effective measures should be taken and correlative policies should be established in order to promote the rehabilitation service in Beijing.

Effect of absorbable poly-D,L-lactide acid rod on development of rabbit epiphyseal plate / 第二军医大学学报

0.05).Both femur bone lengths in 3.2mm group were shorter than those in the 1.5 mm and 2.2 mm groups.No abnormalities of cartilage cells were observed,without obvious histological evidence of inflammation;only nonspecific foreign body reaction and macrophage infiltration were noticed.Conclusion: PDLLA rod itself does not cause any disturbance to the development of the epiphyseal plate.The growth disturbance of epiphyseal plate depends on the area of injured epiphyseal plate;a injured area over 7% of epiphyseal plate may cause the growth disturbance of epiphyseal plate.