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Journal of Experimental Hematology ; (6): 618-621, 2022.
Artigo em Chinês | WPRIM | ID: wpr-928763

RESUMO

With the progress of medical technology, cloning hematopoietic was found to be widely exist in normal people. Because of its clinical significance and prognosis is unclear, it is named clonal hematopoiesis of indeterminate potential(CHIP), which has been detected in blood diseases such as myelodysplastic syndrome and lymphoma, and proven to be related to poor prognosis. Recently, CHIP has been also detected in patients with multiple myeloma (MM). In this article, the definition and influencing factors of CHIP, clinical significance, prognosis and treatment in MM were reviewed.


Assuntos
Humanos , Hematopoiese Clonal , Hematopoese , Mieloma Múltiplo , Mutação , Síndromes Mielodisplásicas
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