RESUMO
BACKGROUND: Obesity is becoming an increasing public health problem. Weight gain in adults causes increased risk of cardiovascular diseases and mortality. The aim of the present study was to investigate the effect of body mass index (BMI) change on cardiovascular risk factors in Korean men. METHODS: This study subjects consisted of 1,169 people, aged 20~71 y at baseline year who had undergone health examinations 2 times for average 8-year period. Height, weight, systolic and diastolic blood pressure, total cholesterol, triglyceride, HDL-C, fasting plasma glucose, and urate were measured. Smoking status, alcohol drinking, and exercise were assessed through self-questionnaire. RESULTS: The baseline mean age was 43.1 6.7 year, the mean weight was 66.8+/-5.2 kg, and the mean BMI was 23.3+/-2.5kg/m2. BMI significantly increased by 0.9 0.04 kg/m2 the during 8-year period. An increase of 1 kg/m2 in BMI was significantly associated with increase of blood pressure, total cholesterol, triglyceride, LDL-C, and urate, and decrease of HDL-C. The risk of cardiovascular diseases was increased with more weight gain. Compared with the lowest quintile of BMI change, the adjusted relative risk of the highest quintile of BMI change for hypercholesterolemia, hypertriglyceridemia, low HDL-C, and hyperuricemia were 5.59 (95% CI: 1.19~26.36), 3.24 (95% CI: 1.53~6.88), 5.16 (95% CI: 2.27~11.77), and 2.18 (95% CI: 1.17~4.06), respectively. The adjusted relative risk for cardiovascular disease tended to increase according to BMI increase (P for trend<0.0001). CONCLUSION: The increase of BMI was significantly associated with worsening of cardiovascular risk factors in Korean men.
Assuntos
Adulto , Humanos , Masculino , Consumo de Bebidas Alcoólicas , Glicemia , Pressão Sanguínea , Índice de Massa Corporal , Doenças Cardiovasculares , Colesterol , Jejum , Hipercolesterolemia , Hipertrigliceridemia , Hiperuricemia , Mortalidade , Obesidade , Saúde Pública , Fatores de Risco , Fumaça , Fumar , Triglicerídeos , Ácido Úrico , Aumento de PesoRESUMO
BACKGROUND: It is generally known that the principle treatment of obesity is life-style modification and behavior therapy for weight reduction. This study was carried out to investigate the effect of office-based education for weight control and behavior modification in overweight patients. METHODS: We selected 119 patients among the overweight or obese (BMI >or=23 kg/m2) patients who visited the Department of Family Medicine at Asan Medical Center. Life styles such as diet, exercise, smoking, and alcohol drinking were evaluated by self-questionnaire. Weight, height, body mass index, waist circumference, waist to hip ratio, and body fat were measured. The patients were divided randomly into two groups, the intervention (n=60) and the control (n=59) group. We educated the intervention group about the importance of weight reduction, life-style modification and provided specific guidelines. Two months later, we measured anthropometric variables and evaluated changes of behavior modification. RESULTS: After two months, 28 patients of the intervention group and 22 patients of the control group were followed up. At the follow-up time, the body weight and waist circumference decreased significantly in the intervention group compared with those of the control group. The exercise time increased significantly in the intervention group compared to the control group. The frequency of fatty meal ingestion decreased significantly in the intervention group. CONCLUSIONS: The office-based education for weight reduction in overweight or obese patients has contributed substantially in changing their life-style and reducing their waist circumference. As a result, we have found that patient education for behavior modification was essential part of comprehensive approach for weight control in overweight patients.