Evaluation of interference factors in creatinine measurement by using new guideline CLSI EP7-A3 / 中华检验医学杂志

Objective:To investigate the interfering factors in the determination of creatinine(Cr) using the American Clinical Laboratory Standards Association (CLSI) EP7-A3 document.Methods:According to the CLSI EP7-A3 document, fresh serum (no hemolysis, lipemia, and jaundice) was used on the day of the experiment and confirmed the interfering substances through the pairing difference experiment and the point-to-point analysis method was used in the dose effect experiment to clarify the difference of interfering substances.Results:Triglyceride (16.94 mmol/L), dobutamine hydrochloride (4.01 μmol/L), ascorbic acid (298 μmol/L) did not interfere with the determination of Cr. Free bilirubin (684 μmol/L), conjugated bilirubin (684 μmol/L), calcium hydroxybenzene sulfonate (144 μmol/L) and hemoglobin (10 g/L) were used as the maximum concentrations of interferences for the dose effect test, the results showed that the above interferences had negative interference on the determination of Cr.Conclusion:According to EP7-A3, it is valuable to evaluate the interference factors of creatinine determination.

Development of risk factors evaluation index system for peri-operative hypothermia / 中国实用护理杂志

Objective To develop a scientific and objective risk factors evaluation index system for peri-operative hypothermia. Methods Based on literature review, the risk factors evaluation index system for peri-operative hypothermia was screened and identified by Delphi method,and the weight was identified through Hierarchy analysis. Results In two rounds of surveys, the rates of questionnaire retrieval were 94.4% and 100.0%, respectively. The authoritative coefficients were 0.83 and 0.84, the coordination coefficients were 0.586 and 0.601, respectively. The index system consisted of 2 first-level indexes and 21 second-level indexes. Conclusions A reliable and scientific risk factors evaluation index system for peri-operative hypothermia was developed. It can be utilized to provide theoretical foundation for the prevention of peri-operative hypothermia.

Long-term results of endolymphatic sac decompression and endolymphatic-mastoid shunting for Meniere's disease / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the efficacy of endolymphatic sac surgery for Meniere's disease, and compare the effects of endolymphatic sac decompression with endolymphatic-mastoid shunting.@*METHOD@#Twelve patients(13 ears) undergoing endolymphatic-mastoid shunting and eleven patients (11 ears) undergoing endolymphatic sac decompression were retrospectively compared for hearing results and vertigo controlled rates. All of them have been followed up for more than two years after surgery.@*RESULT@#According to Chinese Meniere's disease diagnosis and curative effect standard evaluation criteria published in 2006, for vertigo symptom of endolymphatic mastoid shunting group, 9 cases (69.2%) achieved grade A(completely controlled), 4 cases (30.8%) achieved grade B (fundamentally controlled). There were 8 cases (72.7%) with grade A, 2 cases (18.2%) with grade B and one case (9%) with grade C among 11 patients who received endolymphatic sac decompression. There was not statistically significant differences in postoperative speech pure tone average and vertigo controlled rate between the two groups.@*CONCLUSION@#Endolymphatic sac decompression and endolymphatic-mastoid shunting are effective management with less complication for intractable Meniere's disease. Particularly, the vertigo symptoms were controlled significantly. Patients with Meniere's disease in advanced clinical stages may also be relieved.

Long-term results of endolymphatic sac decompression and endolymphatic-mastoid shunting for Meniere's disease / 临床耳鼻咽喉头颈外科杂志

Objective:To investigate the efficacy of endolymphatic sac surgery for Meniere's disease,and compare the effects of endolymphatic sac decompression with endolymphatic-mastoid shunting.Method:Twelve patients(13 ears)undergoing endolymphatic-mastoid shunting and eleven patients (11 ears) undergoing endolymphatic sac decompression were retrospectively compared for hearing results and vertigo controlled rates.All of them have been followed up for more than two years after surgery.Result:According to Chinese Meniere's disease diagnosis and curative effect standard evaluation criteria pubilished in 2006,for vertigo symptom of endolymphaticmastoid shunting group,9 cases(69.2%) achieved grade A(eompletely controlled),4 cases (30. 8%) achieved grade B(fundamentally controlled).There were 8 cases(72.7%)with grade A, 2 cases (18.2%)with grade B and one case(90% ) with grade C among 11 patients who received endolymphatic sac decompression.There was not statistically significant differences in postoperative speech pure tone average and vertigo controlled rate between the two groups.Conslnsion:Endolymphatic sac decompression and endolymphatic-mastoid shunting are effective management with less complication for intractable Meniere's disease. Particularly,the vertigo symptoms were controlled signifisantly. Patients with Meniere's disease in advanced clinical stages may also be relieved.

Experimental Observation of Spontaneous Otoacoustic Emissions and Cochlear Microphone Potential in Guinea Pigs / 听力学及言语疾病杂志

The spontaneous otoacoustic emissions(SOAEs) and spontaneous cochlear microphone potential (SCM) were observed in 8 guinea pigs from 168 normal guinea pigs. Second and third harmonics of SOAE had been observed in three animals. The distortion product otoacoustic emissions(2f1-f2) were created with an external tone as f2 and the SOAE as f 1 in 6 animals , SOAE were suppressed by contralateral broadband noise stimulation and enhanced by strychnine . The suppression tuning curve was similar to the two tone suppression. The results indicate that SOAE and SCM are spontaneous electromotile vibration of outer hair cells. The model of spontaneous vibration and characteristic of audiology is the same as that of hearing of external tone and it can be modulated by efferent system.

Labyrinthine Ossification (Report of 2 Cases) / 听力学及言语疾病杂志

Two cases of labyrinthine ossification were founded in temporal bone exploration and in cochlear implantation. One was caused by temporal bone fracture, the other had bilateral profound sensorineural hearing loss but the reason for labyrinthine ossification was unknown. In this case,unilateral total labyrinthine ossification was not confirmed in preoperative CT scan.